Mauna Kea Technologies

Centre National De La Recherche Scientifique

Commissariat &#xc0; L'&#xc9;nergie Atomique Et Aux &#xc9;nergies Alternatives

Université Pierre Et Marie Curie (Paris 6)

UniversitÉ´de Rouen

Université Pierre Et Marie Curie

Geneviève Bourg-Heckly

Alexandre Loiseau

Eric Peltier

Nicolas Boularot

Bertrand Viellerobe

Magalie Genet

François Lacombe

Anne Planat-Chretien

Michel Berger

Benjamin Abrat

Sandrine Vilette

Veronica Sorgato

Luc Thiberville

Charlotte Emain

Charlotte Cave

Véronique Dentan

Christine Vever-Bizet

Florence Jean

Véronica Sorgato

A method and a device allow optical properties of a sample to be estimated. The method includes the illumination of the sample by a first light source, and the formation of an image of the sample thus illuminated, on the basis of which a first optical property is estimated, at various points on a surface of the sample. The method also includes measuring an auxiliary optical property of the sample and estimating the first optical property, taking account of the auxiliary optical property measured on the sample.

Method and device for estimating optical properties of a sample

A method for imaging a tissue includes collecting a light signal from at least part of said tissue, using a fiber optic probe for fluorescence imaging, wherein the fiber optic probe comprises a plurality of optic fibers, and wherein a distal tip of the fiber optic probe is placed at a distance from said tissue, said imaging being made confocal at a proximal tip of said fiber optic probe. A fluorescence imaging system includes an endoscope equipped with a working channel, in which a fiber optic probe has been inserted, wherein the fiber optic probe is movable between a retracted position and at least one position of extension, said fiber optic probe comprising a plurality of optic fibers for performing imaging of a tissue, said imaging being confocal via a processor located at a proximal tip of said fiber optic probe.

Use of a system for imaging by fiber-optic confocal fluorescence in vivo in situ, system and method for imaging by fiber-optic confocal fluorescence in vivo in situ

The invention relates to a method for producing a fluorescent fiber image of a sample, wherein a sample is scanned with the aid of an excitation signal; the fluorescent signal emanating from the sample is detected, wherein the excitation signal and fluorescent signal use the same optical path; the optical path is used to excite at least two fluorophores contained in the sample; a final image is produced, including areas that are colored according to the at least two fluorophores. The multimarking according to the invention makes it possible to simultaneously acquire two images in two different wavelength bands. The system according to the invention can comprise a spectrometer for spectral quantification of the fluorescent signal.

Multimarking fibre-type fluorescence microscopic imaging method and system

An equipment includes an excitation source (), elements for injecting () an excitation signal produced by the source in an ordered bundle () of flexible optical fibers, elements for analyzing () an emitted autofluorescence signal. The equipment also includes at the output of the optical fiber bundle () an optical head () designed to be placed in contact with the biological tissue (), the optical head being equipped with optical elements adapted to cause the excitation signal output from the bundle () to converge into a subsurface analyzing zone (), the same optical fiber(s) used for excitation of the bundle () being used for detecting the signal emitted by the subsurface analyzing zone, elements (D) placed upstream of the injection elements () being further provided to separate the wavelength of the excitation signal and the wavelength of the autofluorescence signal.

Equipment for subsurface autofluorescence spectroscopy

Growing community of inventors

Paris, France

Geneviève Bourg-Heckly