Medivir Ab

Janssen R&d Ireland

Janssen Products, LP

Genadiy Kalayanov

Horst Wahling

Staffan Torssell

David Bernard Smith

Bart Rudolf Romanie Kesteleyn

Bengt Bertil Samuelsson

Hans Kristian Wallberg

Nils-Gunnar Johansson

Anna Winqvist

Wim Bert Griet Schepens

Johannes Wilhelmus J Thuring

Kevin Parkes

Jörg Kurt Wegner

Horst Wähling

Joerg Kurt Wegner

Joseph Armstrong Martin

The invention provides compounds of the formula: wherein B is a nucleobase selected from the groups (a) to (d): and the other variables are as defined in the claims,which are of use in the treatment or prophylaxis of hepatitis C virus infection, and related aspects.

HCV polymerase inhibitors

The invention provides compounds of the formula:  

HIV inhibitors of formula (I) wherein Ris halo, Calkoxy, trifluoromethoxy; Ris a group of formula (A); Ris a group of formula (B); Ris a group of formula (C); n is 0 or 1; A is CH or N; Rand Rare hydrogen, Callyl, halo; Rand Rare Callyl or Calkoxy-Calkyl; Ris Callyl, cyclopropyl, trifluoromethyl, Calkoxy, or dimethylamino; Ris hydrogen, Calkyl, cyclopropyl, trifluoromethyl, Calkoxy, or dimethylamino; pharmaceutically acceptable addition salts and solvates thereof; pharmaceutical compositions containing these compounds as active ingredient and processes for preparing said compounds.

5-amino-4-hydroxypentoyl amides

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Huddinge, Sweden

Genadiy Kalayanov