Life Technologies As

Life Technologies Corporation

Dynal Biotech Asa

Invitrogen Dynal As

Thermo Fisher Scientific Geneart Gmbh

Invitrogen Corporation

Sintef

Ge Healthcare Bio-sciences Ab

University of Southern Denmark

Geir Fonnum

Steven Menchen

Nini Kjus

Astrid Evenroed Molteberg

Grete Irene Modahl

Wolfgang Hinz

Carl Williams Fuller

Luisa Andruzzi

Jo Aaserud

Elin Marie Aksnes

Ellen Weng

Lars Kilaas

Arvid Trygve Berge

Ruth Schmid

Synne Larsen

M Talha Gokmen

Diem Tran

Hee Chol Kang

Dmitriy Gremyachinskiy

Bruce Branchaud

Lai-Qiang Ying

Rolf Nordal

Alfred Lui

Talha M Gokmen

Diem Thuy Thi Tran

Muhammed Talha Gokmen

Darren Ellis

Heidi Johnsen

Tom-Nils Nilsen

Jon Olav Bjorgum

Wilhelm Glomm

Henning Pettersen

Solveig Staale

Nils Pontus Lundberg

Finn Hansen

Oddvar Aune

Prasanna Krishnan Thwar

John Ugelstad

Lily Lu

Per Martin Stenstad

Erling Sigurd Finne

Guobing Xiang

Turid Ellingsen

Korbinian Heil

Julian Cockbain

Svein Tøgersen

Xiquan Liang

Frank Notka

Axel Trefzer

Thomas Poehmerer

Robert Marshall Pope

Nini Kjus Hofsløkken

Kristian Andersson

Preben Cato Mørk

Lene Husaboe

Pontus Lundberg

Arne Jørgedal

Silje Nordbø

John Bjørgum

Torkel Stene

Elisabeth Breivold

Astrid Evenrød Molteberg

Tollef Taarneby

Federico Katzen

Turid Ellingsen, Deceased

John Ugelstad, Deceased

Viola Ugelstad, Legal Representative

Silje Lien

Per Nils Pontus Lundberg

Arvid Tryge Berge, Legal Representative

Lise Liljeroth

Tollef Tårneby

Arne Jorgedal

Phillip Kuhn

Silje Nordbo

John Bjorgum

Andreas Zeidler

Stine Bergholtz

Ansgar Romig

Finn Knut Hansen

Astrid Evenrod Molteberg

Solveig Marie Staale

Nini Kjus Hofsloekken

Jon Olav Bjoergum

Kristian H Andersson

Steven M Menchen

Muhammed Talha GÖKMEN

Darren James Ellis

Nini Hofslokken Kjus

Silje Steinbakk Nordbo

A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.

Hydrophilic polymeric particles and methods for making and using same

This invention relates to monodisperse cross-linked hydrogel polymer particles comprising a polymer formed from (a) a hydrophilic vinylic monomer; and (b) a crosslinker comprising at least two vinyl groups. The invention also relates to monodisperse seed particles with a Z-average diameter of from 100 nm to 1500 nm that comprise a plurality of non-crosslinked oligomers of poly N,N-dimethylacrylamide. Also provided are methods of forming the monodisperse cross-linked hydrogel polymer particles and monodisperse seed particles.

Inverse Ugelstad particles

This invention relates to monodisperse magnetic hydrogel polymer particles comprising a magnetic material and a polymer formed from (a) a hydrophilic vinylic monomer having a log P(log P) of less than about 0.5; and (b) a crosslinker comprising at least two vinyl groups. The invention also relates to monodisperse coated hydrogel polymer particles comprising a polymer formed from (a) a hydrophilic vinylic monomer having a log P(log P) of less than about 0.5; and (b) a crosslinker comprising at least two vinyl groups; and a coating. Also provided are methods of forming the monodisperse magnetic hydrogel polymer particles and monodisperse coated polymer particles.

Polymeric particles

A method for processing a nucleic acid, in which the nucleic acid is exposed to an aqueous medium which includes a polyol in sufficient proportion for at least a portion of the nucleic acid to enter or remain in an extra-solution phase. Thus, a polyol may be used to bind a nucleic acid which is in solution to a solid support or to wash a nucleic acid on a solid support whilst maintaining it on the support. The polyol may for example be a C-Calkanediol.

Nucleic acid preparation method

Inverse ugelstad particles

This invention relates to polymer particles for solid phase oligonucleotide synthesis. The oligonucleotide may be linked to the particle via a linker having an amide-oligoethyleneglycol-amine structure. The particles may be considered to act as a solid support during the oligonucleotide synthesis. Also disclosed are processes for preparing such polymer particles, compositions and systems comprising such particles, and uses thereof.

Solid support

A polymer substrate, such as a polymer coating or a polymer hydrogel network, includes carboxyl moieties that can be used as conjugation sites to which receptor or analyte molecules can be attached. In an example, the polymer substrate includes a polyacrylamide polymer network having alkanoic acid moieties or derivatives thereof, which can react with carboxyl activating compounds to provide an activated alkanoate moieties on the polyacrylamide network. Amine-terminated nucleic acids can react with the activated alkanoate moieties to capture the nucleic acid to the polymer network through an alkylamide moiety.

Conjugation of carboxyl functional hydrophilic beads

The disclosure generally relates to compositions and methods for the production of nucleic acid molecules. In some aspects, the invention allows for the microscale generation of nucleic acid molecules, optionally followed by assembly of these nucleic acid molecules into larger molecules. In some aspects, the invention allows for efficient production of nucleic acid molecules (e.g., large nucleic acid molecules such as genomes).

High efficiency, small volume nucleic acid synthesis

A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of monomer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.

A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.

Polymer substrates formed from carboxy functional acrylamide

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Fjellhamar, Norway

Geir Fonnum