Katholieke Universiteit Leuven

Rijksuniversiteit Groningen

Gea Schuurman-Wolters

Giovanni Maglia

Mikhael Soskine

Annemie Biesemans

Bert Poolman

Veerle Van Meervelt

A method for detecting an analyte in a sample includes the steps of obtaining a nanopore sensor comprising a nanopore and a protein adaptor internalized in the lumen of the nanopore, adding a sample comprising an analyte to the cis side or the trans side of the nanopore, and measuring conductance across the nanopore. A change in conductance after adding the sample indicates the analyte is present in the sample and has bound to the protein adaptor. Nanopore sensors comprise a nanopore and a protein adaptor internalized in the lumen of the nanopore. The protein adaptor is a functional enzyme or ligand-binding protein.

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Nietap, Netherlands

Gea Schuurman-Wolters