Centre National De La Recherche Scientifique

Ecole Normale Superieure De Lyon

Universite Claude Bernard – Lyon1

Université Pierre Et Marie Curie (Paris 6)

Université Paris Diderot-Paris 7

Université Pierre Et Marie Curie

Gaël Yvert

Jérôme Bibette

Laurent Boitard

Nicolas Bremond

Jens Hasserodt

Jean-Marie Baudry

Denis Cottinet

Maxime Prost

Corentin Gondrand

Gérard Triqueneaux

The invention relates to novel glycosidase substrates of formula (I), wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R'9, V, X, Y and Z are as defined in claim, and a method for detecting the presence of a catalytically active glycosidase by means of one of said substrates. 

Fluorogenic glycosidase substrate and associated detection method

This method comprises bringing drops to be separated into contact with an interface () suitable for allowing an osmotic equilibrium between the content of each drop to be separated. The method comprises an osmotic flow between the drops (A) of the first group of drops through the interface () in order to modify the density of each drop (A) of the first group of drops and the separation of the drops (A,B) according to the density thereof or a combination of the density and the volume in order to isolate the drops (A) of the first group of drops from the drops (B) of a second group of drops.

Method for high-throughput screening of drops by osmotic exchange and density variation

Growing community of inventors

Saint Genis Laval, France

Gaël Yvert