The Texas A&m University System

Scott & White Healthcare

Temple Therapeutics, Inc.

Gavin W Roddy

Darwin J Prockop

Robert Rosa

Barry A Berkowitz

Joo Youn Oh

The present invention encompasses methods and compositions for treating an ocular disease, disorder or condition in a mammal. The invention includes a population of mesenchymal stromal cells that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties. The invention includes administration of TSG-6, STC-1, or a combination thereof to the ocular as a treatment for an ocular disease, disorder or condition in a mammal.

Adult stem cells/progenitor cells and stem cell proteins for treatment of eye injuries and diseases

The present invention encompasses methods, compositions, and devices for treating an ocular disease, disorder or condition in a mammal. The invention includes polypeptides that possess anti-inflammatory, anti-apoptotic, immune modulatory and anti-tumorigenic properties, and their application in the treatment of eye disease, particularly diseases of the retina. In particular aspects, the invention includes administration of a therapeutic polypeptide such as a stanniocalcin family member protein for the treatment of an eye disease. Also included are fusion proteins and cells stimulated or modified to express the therapeutic polypeptides as set forth herein.

Stanniocalcin-1 (STC-1) therapy for treatment of retinal diseases

Protein therapy for treatment of retinal diseases

Protein therapy for corneal inflammation, epithelial wound healing, and photoreceptor degeneration

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Temple, TX, United States of America

Gavin W Roddy