Novartis Ag

Nortev Limited

Gavan O'Sullivan

Declan Moran

John Sylvester Power

James B Fink

Niall Smith

Paul Dunne

Ehud Ivri

Keith Gibbons

Donal Devery

An aerosol generator assembly comprising a vibratable piezo ceramic body () having first and second opposing sides, an aperture (o) defined in the vibratable body and extending through the body from the first side to the second side and having a layer of electrical contact material on each side of the vibratable body, the vibratable body being vibratable by application of an electrical signal thereto; a vibratable member () with pores defined therein, the vibratable member mounted across the aperture; and an electrical contact material free-zone () is provided on at least one side of the body about the aperture, characterized in that the electrical contact material free-zone and the vibratable member are dimensioned so that the vibratable member is mountable directly onto the vibratable body on top thereof within the electrical contact material free-zone such that a gap area free of electrode contact material is formed between the terminating edge of the electrical contact material and the periphery of the vibratable member.

Aerosol generator assembly

A nebulizer to deliver a medicament that includes a housing having a reservoir for the medicament, an aerosol generator that can be supplied the medicament from the reservoir, where the generator aerosolizes at least a portion of the medicament into an aerosol, a gas venting inlet to permit a gas to enter the nebulizer and form a mixture with the aerosol, and a passage through which the mixture of the aerosol and the gas is delivered to an outlet port of the nebulizer.

Nebuliser for the production of aerosolized medication

A system for intermittent delivery of an aerosolized medicament is disclosed. The system may include an aerosol generator, a controller and a conduit. The aerosol generator may be configured to aerosolize a medicament. The controller may be configured to receive physiological characteristic information about a patient, and control the aerosol generator based at least in part on the physiological characteristic information. The conduit may be configured to supply the aerosolized medicament to the patient's airway.

Methods and systems for operating an aerosol generator

A method of treating a patient with a pulmonary disease, where the method includes delivering a dose of aerosolized medicament intermittently to a ventilator circuit coupled to the respiratory system of the patient. Also, a method of treating a patient with a pulmonary disease, where the method includes taking the patient off a ventilator, and administering to the patient, a nebulized aerosol comprising from about 100 &#x3bc;g to about 500 mg of a medicament. Additionally, an aerosolized medicament for the treatment of a pulmonary disease, where the medicament includes amikacin mixed with an aqueous solution having an adjusted pH from about 5.5 to about 6.3. The pH is adjusted by adding hydrochloric acid and sodium hydroxide to the aqueous solution.

Growing community of inventors

Gort, Ireland

Gavan O'Sullivan