Smithkline Beecham Corporation

Glaxosmithkline LLC

Gary Woodnutt

Eric Hunt

Steven Dabbs

Francis Dominic Sanderson

Colin Henry Frydrych

Valerie Joan Berry

Peter Lawrence DeMarsh

Susan B Dillon

The present invention relates to pleuromutilin derivatives, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medical therapy, particularly antibacterial therapy.

Pleuromutilin derivatives as antimicrobials

This invention relates to a method for the prophylaxis of or reducing the severity of post-viral bacterial infection by administering a PDE 4-specific inhibitor prior to or during the course of a viral infection or thereafter during the course of the bacterial infection.

Use of PDE 4-specific inhibitors to reduce the severity of a bacterial infection after a respiratory viral infection

Growing community of inventors

Chester Springs, PA, United States of America

Gary Woodnutt