Other

Wyeth

Gary Sondermann Grubb

Jay Edward Wrobel

Andrew Fensome

James Patrick Edwards

Lin Zhi

Todd Kevin Jones

Christopher Michael Tegley

Puwen Zhang

Eugene Anthony Terefenko

John W Ullrich

Diane Deborah Harrison

Richard Winneker

Arthur Attilio Santilli

Horace Fletcher, Iii

Andrew Q Viet

Lori L Miller

Reinhold H W Bender

Reinhold R W Bender

Casey Cameron McComas

Edward George Melenski

Jeffrey Curtis Kern

Mark A Collins

Michael Anthony Marella

Valerie A Mackner

Ginger Dale Constantine

A method of contraception is provided which involves delivery of 21 to 27 consecutive days of a progestin in the absence of an estrogen or other steroidal compound, followed by 1 to 7 days without an effective amount of an active agent. Also described is a pharmaceutically useful kit to facilitate delivery of this regimen.

Cyclic progestin regimens and kits

The present invention provides methods of inducing contraception which includes delivering to a female a composition containing a compound of formula I, or tautomers thereof, in a regimen which involves delivering one or more of a selective estrogen receptor modulator, wherein formula I is: and wherein R-Rand Qare defined as described herein. Methods of providing hormone replacement therapy and for treating carcinomas, dysfunctional bleeding, uterine leiomyomata, endometriosis, and polycystic ovary syndrome is provided which includes delivering a compound of formula I and a selective estrogen receptor modulator are also described.

Methods of treating hormone-related conditions using thio-oxindole derivatives

Pyrrole-oxindole derivatives useful as progesterone receptor antagonists, and methods for preparing the same, are provided. Pharmaceutical compositions containing these derivatives are described, as is the use thereof in contraception and hormone-related conditions.

Progesterone receptor modulators comprising pyrrole-oxindole derivatives and uses thereof

The present invention provides a contraceptive kit which helps to overcome or ameliorate the problem of breakthrough bleeding and spotting associated with lowest dose (15-20 ug EE) estrogen contraceptives.

Starter kit for low dose oral contraceptives

The present invention provides methods of inducing contraception which includes delivering to a female a composition containing a compound of formula I or formula II, or tautomers thereof, in a regimen which involves delivering one or more of a selective estrogen receptor modulator, wherein formula I is: and wherein R&#x2013;Rand Qare defined as described herein. Methods of providing hormone replacement therapy and for treating carcinomas, dysfunctional bleeding, uterine leiomyomata, endometriosis, and polycystic ovary syndrome is provided which includes delivering a compound of formula I and a selective estrogen receptor modulator are also described.

Methods of treating hormone-related conditions using cyclothiocarbamate derivatives

Growing community of inventors

Newtown Square, PA, United States of America

Gary Sondermann Grubb