Essential Medical, Inc.

Teleflex Life Sciences Pte. Ltd.

Salviac Limited

Vascular Therapies, Inc.

Estrogen Vascular Technology, LLC

Arrow International Limited

Gary Roubin

Greg A Walters

Michael Nispel

Piyush Arora

Michael Austin Dotsey

Nicholas N Kipshidze

Paul Gilson

Mike Dotsey

Sriram S Iyer

Martin B Leon

Victor V Nikolaychik

Jeffrey Warren Moses

Gishel New

A closure device for sealing a percutaneous puncture in a wall of a body passageway, the closure device including at least one of a toggle configured to engage an interior surface of the body passageway or a plug configured to engage an exterior surface of the body passageway and a guide wire configured to extend from an outside of the body to inside the body passageway, wherein at least one of the toggle and the plug is associated with the guide wire.

Instrument and methods for surgically closing percutaneous punctures

Devices and methods for reducing, eliminating, preventing, suppressing, or treating tissue responses to hemostatic devices e.g., biological sealants or vascular procedures are disclosed. The invention employs a combination of resorbable, biocompatible matrix materials and a variety of therapeutic agents, such as antiproliferatives or antibiotics, applied to a vascular puncture or incision to achieve hemostasis following diagnostic or interventional vascular catheterizations and to treat neointimal hyperplasia and stenosis. A matrix of a material such as collagen provides a reservoir of a therapeutic agent such as rapamycin (sirolimus) and its derivatives and analogs for delivery at a tissue site at risk for vasculoproliferation, infection, inflammation, fibrosis or other tissue responses.

Medical implants and methods for regulating the tissue response to vascular closure devices

A rapid exchange stent delivery catheter for delivery and deployment of a stent has a catheter shaft having a guidewire lumen defined by a passageway with an entrance and an exit. The stent is of a shape memory metallic alloy and is constrained by a sheath. The sheath has an elongate slot aligned with the guidewire lumen entrance so that a guidewire is not obstructed during movement of the sheath to deploy the stent. The sheath is pulled back linearly by a thumbscrew mechanism to deploy the stent.

Delivery catheter

A method of treating or preventing vascular disease in a living organism. The method includes delivering an effective amount of a composition including a sex hormone, anti-hormone, sex-hormone agonist, steroid-hormone inhibitor/antagonist (partial or full), selective estrogen receptor modulator (SERM), or a combination thereof, to an affected area of a living organism.

Apparatus and method for delivering compounds to a living organism

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New York, NY, United States of America

Gary Roubin