Amplipharm Pharmaceuticals, LLC

Amplipharm Pharmceuticals, LLC

Gary Payton

Jeff Bryant

Frank Francavilla

A kit comprising a device for dosing and dispensing a dose of a non-liquid medicine that is readily dispersible in an aqueous solution suitable for oral administration, preferably a temozolomide formulation that can be titrated readily and accurately.

Device and kit for dosing and dispensing non-liquid medicine

The present invention relates to a solid pharmaceutical composition of temozolomide that has good and consistent flowability as a powder and taste masking and is readily dispersible in an aqueous solution suitable for oral administration, e.g., as a dry sprinkle. This permits patients and healthcare workers to accurately measure doses and safely dispense the drug.

Temozolomide powder formulation

A device for dosing and dispensing a dose of a non-liquid medicine that comprises a body connectable to a container containing an amount of a non-liquid medicine. When the body is connected with the container, an amount of the non-liquid medicine may be transferred from the container to at least one chamber defined within the body. In a preferred embodiment, two chambers are defined within the body, each having a different predetermined size (i.e., volume). A user may set the amount of the non-liquid medicine to be transferred using a plunger rod slideably located within the at least one chamber, or with each of the two chambers. A kit comprises the device and a non-liquid medicine that is readily dispersible in an aqueous solution suitable for oral administration, preferably a temozolomide formulation that can be titrated readily and accurately.

The present invention relates to a solid pharmaceutical composition of temozolomide that has good and consistent flowability as a powder and taste masking and is readily dispersible in an aqueous solution suitable for oral administration, e.g., as a dry sprinkle. This permits patients and healthcare workers to accurately measure doses.

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Johns Creek, GA, United States of America

Gary Payton