Novartis Finance Corporation

Syngenta Investment Corporation

Ciba-geigy Corporation

Novartis Corporation

Syngenta Investments, Inc.

Gary M Pace

Michael G Koziel

Nalini M Desai

Gregory W Warren

Martha S Wright

Erik M Dunder

Karen L Launis

John L Dawson

Kelly S Lewis

Stephen V Evola

Janet L Suttie

Cindy G Bowman

Steven J Rothstein

Lyle Dean Crossland

Ellis J Merlin

Nadine B Carozzi

Vance C Kramer

Vance Cary Kramer

Moez Rajabali Meghji

Annick Jeanne De Framond

Bruce Wayne Skillings

James O Linder

Cindy Boyce

Robert L Miller

Christopher P Clucas

Andreas H Tanner

Steve Evola

Gilles Pollini

Terry Ray Colbert

Francis P Cammack

Francis E Cassagne

Alan W Mousel

Jan Suttie

Albert R Hornbrook

DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from . Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.

Transgenic maize seed and method for controlling insect pests

Methods for transformation of maize with nucleic acid sequences of interest are disclosed. The method involves subjecting immature zygotic embryos or Type I callus to high velocity microprojectile bombardment. The method is capable of producing transformed maize lines of commercial importance and their hybrid combinations.

Method of producing transgenic maize using direct transformation of commercially important genotypes

DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from,. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.

Synthetic DNA sequences having enhanced insecticidal activity in maize

DNA sequences optimized for expression in plants are disclosed. The DNA sequences preferably encode for an insecticidal polypeptides, particularly insecticidal proteins from Bacillus thuringiensis. Plant promoters, particular tissue-specific and tissue-preferred promoters are also provided. Additionally disclosed are transformation vectors comprising said DNA sequences. The transformation vectors demonstrate high levels of insecticidal activity when transformed into maize.

Synthetic DNA sequence having enhanced insecticidal activity in maize

Nucleic acid promoter fragment isolated from a plant tryptophan synthase

Synthetic DNA sequence having enhanced activity in maize

Growing community of inventors

Cary, NC, United States of America

Gary M Pace