Medtronic Ardian Luxembourg S.a.r.l.

Gary Kelly

Mark Gelfand

Denise Marie Zarins

Mark S Leung

John Kelly

Karun D Naga

Brian Kelly

Fiachra Sweeney

Grace Kelly

Eric Ryba

Lana Woolley

Barry Mullins

Naomi Buckley

Michael Cummins

Danny Donovan

Luke Hughes

Vincenzo Tilotta

Benjamin J Clark

Roman Turovskiy

Stephen Nash

Michael Turovskiy

Gwenda Francis

Francesco Piccagli

Micheal Moriarty

Gwenda McMullin

Ronan Wood

Seamus Ledwith

Neuromodulation cryotherapeutic devices and associated systems and methods are disclosed herein. A cryotherapeutic device configured in accordance with a particular embodiment of the present technology can include an elongated shaft having distal portion and a supply lumen along at least a portion of the shaft. The shaft can be configured to locate the distal portion intravascularly at a treatment site proximate a renal artery or renal ostium. The supply lumen can be configured to receive a liquid refrigerant. The cryotherapeutic device can further include a cooling assembly at the distal portion of the shaft. The cooling assembly can include an applicator in fluid communication with the supply lumen and configured to deliver cryotherapeutic cooling to nerves proximate the target site when the cooling assembly is in a deployed state.

Neuromodulation cryotherapeutic devices and associated systems and methods

Cryotherapeutic systems configured for refrigerant recompression and associated devices, systems, and methods are disclosed herein. A cryotherapeutic system configured in accordance with a particular embodiment includes a high-pressure line, a low-pressure line, a recompression unit, and a cryo-catheter. The recompression unit increases the pressure of refrigerant from the low-pressure line to the high-pressure line to a treatment pressure sufficient for cryogenic alteration of tissue. The high-pressure line and the low-pressure line include, respectively, a first connector and a second connector. The cryo-catheter includes a shaft, a supply lumen in the shaft that is coupled to the first connector, an exhaust lumen in the shaft that is coupled to the second connector, and a cryo-applicator attached to the shaft having a cooling chamber configured to receive refrigerant from the supply lumen and to return refrigerant via the exhaust lumen to the low-pressure line.

Refrigerant supply system for cryotherapy including refrigerant recompression and associated devices, systems, and methods

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Windsor, CA, United States of America

Gary Kelly