The Johns Hopkins University

Gary Gerstenblith

Gordon Tomaselli

Chao-Wei Hwang

Robert G Weiss

Peter V Johnston

Jeffrey A Brinker

Steven P Schulman

Zhiyong Xia

Virginia E Bogdan

George L Coles

Jason J Benkoski

Sheldon H Gottlieb

Jeffrey A Spaeder

Edward K Kasper

James G Palmer

Philip R Thorne

Certain embodiments according to the present invention provide sleeve devices suitable for a wide range of therapeutic uses. In accordance with certain embodiments, the therapeutic sleeve device includes a nanofiber fabric assembly, which defines a plurality of pores, and at least one layer of cells embedded in the nanofiber fabric assembly.

Cell impregnated sleeve for paracrine and other factor production

A method for promoting healing of tissue by delivering a bioreactor into a subject is provided. The bioreactor is an enclosed housing with paracrine factor producing cells enclosed within the housing. The housing is impermeable to the paracrine factor producing cells, impermeable to immunological cells outside of the housing, and permeable to paracrine factors produced by the paracrine factor producing cells. The paracrine factors produced by the paracrine factor producing cells are released out of the housing to promote healing of the tissue.

Methods for promoting healing of tissue

The present invention is an outpatient monitoring system which enables patients to interact with a health care provider using a standard telephone. A patient is presented with a series of condition-appropriate questions. Based upon the patient responses, additional questions are posed on a real-time dynamic basis. In addition, certain general questions from a predefined set of questions are asked of the patient in a rotating manner to ensure that there is variety with each telephone session. Further, the question sets can be recorded in the voice of the patient's clinician, or other person familiar to the patient, so that a familiar voice is heard by the patient, thereby personalizing the medical experience.

Method and system for outpatient monitoring

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Reisterstown, MD, United States of America

Gary Gerstenblith