Philip Morris USA Inc.

Philip Morris Inc.

Philip Morris Products S.a.

Gary E Grollimund

Donald L Brookman

Walter Allen Nichols

Douglas D McRae

Ulysses Smith

Barry Scott Smith

Sudarsan Srinivasan

F Murphy Sprinkel, Jr

Steven Frederick Spiers

Kenneth A Cox

Everett C Grollimund

Niranjan Maharajh

David Ammann

H Cary Longest

Tung Tien Nguyen

Herbert Carrington Longest, Jr

Roy E VanDerLinden

Edwin Waldbusser

Douglas D Mcrae

Douglas Mcrae

Don Brookman

Douglas D Mcrea

A drug delivery system, which includes an aerosol generator unit, a pumping unit, a flow tube, at least one condensate collector and an aerosol transition adapter. The aerosol generator forms an aerosol from a liquid formulation, which is partially volatilized. The pumping unit supplies the liquid formulation to the aerosol generator unit and a flow tube having an inlet end in fluid communication with an outlet of the aerosol generator unit and an outlet adapted for connection to a patient interface, which supplies ventilation gas to a patient's lungs. The system also includes at least one condensate collector adapted to collect condensed liquid or liquid produced by the aerosol generator unit, and a transition adapter arranged to mix aerosol produced by the aerosol generator unit with heated air or ventilation gas and direct the mixed aerosol into the inlet end of the flow passage.

Continuous high pressure delivery system

An aerosol generator such as a hand-held inhaler and method of delivering aerosol to a user inhaling on an outlet of a mouthpiece when a pressure drop is detected within the mouthpiece. A medicated fluid passing through a capillary passage is heated sufficiently to vaporize the fluid and form the aerosol by condensation of the vaporized fluid as it admixes with air. Air is supplied to the mouthpiece through an air passage which is initially closed during detection of the pressure drop. A metering chamber allows consistent delivery of precise doses of fluid to the capillary passage. The pressure drop is detected before air is supplied to the mouthpiece with the result that the aerosol can be quickly delivered to the user as the user begins to inhale on the mouthpiece. The quick delivery of aerosol provides more efficient use of the user's lung capacity.

Aerosol generator for drug formulation

A piston pump delivers precise and repeatable volumes of a fluid from a reservoir to a downstream component, and includes a piston that is rotatably and reciprocally mounted within a cylinder. The outer periphery of the piston forms an interference fit with the inner periphery of the cylinder. At least one groove is formed in the outer periphery of the piston, with the groove defining a precise volume between the piston and the cylinder, and extending in an axial direction of the piston. The cylinder includes an inlet port for providing fluid communication between a reservoir and the at least one groove when the piston is in a first position, and an exit port circumferentially spaced from the inlet port for providing fluid communication between the at least one groove and a downstream component when the first piston is rotated to a second position where the at least one groove is aligned with the exit port.

Piston pump useful for aerosol generation

An aerosol generating device generates an aerosol having a desired particle size by passing a liquid through a flow passage heated to convert the liquid into a vapor. The flow passage includes an outlet section that controls the exit velocity of the vapor and produces an aerosol with a desired particle size. The aerosol generator can be incorporated in a hand held inhaler, and the liquid can include a medicament, which is delivered to a targeted portion of the lung using the inhaler.

Aerosol generating device and method of use thereof

An aerosol generator and methods of delivering aerosol to a user inhaling on a mouthpiece when a pressure drop is detected within the mouthpiece are disclosed. A medicated fluid passing through a capillary passage is heated to vaporize the fluid and form the aerosol by condensation or mixture of the vaporized fluid with admixed air. A metering chamber allows consistent delivery of precise doses of fluid to the capillary passage. Once the pressure drop is detected, aerosol can be quickly delivered to the user as the user begins to inhale on the mouthpiece. The quick delivery of aerosol provides more efficient use of the user's lung capacity.

Aerosol generator for drug formulation and methods of generating aerosol

Improved systems for optical inspection are provided. The improved systems use modified camera boxes to provide increased, and more uniform, illumination of the objects being inspected through the use of illuminator windows. The lens arrangement of the improved camera boxes is contained within a self-contained, sealed housing that is separate from the camera to prevent particle contamination of the lens arrangement and provide improved flexibility during installation of the camera boxes on the inspection systems. The self-contained housing also provides for a reduction in the space required for the camera boxes. The light receiver of the housing is provided with the capability for preventing particle contamination of the receiver itself.

Systems for optical inspection

The entire cylindrical surface of a cylindrical object such as a cigarette is optically inspected by first inspecting at least 180.degree. of the circumference of a first side of the surface, and then inspecting at least 180.degree. of the circumference of the other side. Each of the inspection stations illuminates more than 180.degree. of the circumference and images the surface from two angularly spaced directions to ensure that at least 180.degree. of the circumference is seen at each station. Any object having a defective image is automatically rejected from the apparatus, and the images and other statistical information regarding the performance of the system are displayed by the system. The images are formed in such a way as to greatly increase the speed at which the inspection system operates so that it can keep up with the very high rates at which objects such as cigarettes are made in modern machinery (e.g., approximately 10,000 cigarettes per minute). The images are analyzed using techniques which make possible the detection of very small defects and also compensate for possible nonuniform illumination of the objects in the circumferential direction.

Systems for optically inspecting cylindrical surfaces

A system is provided for packing, shipping and automated unloading of stacks of box blanks so as to minimize damage to the box blanks and facilitate the insertion of the box blanks into an automated packaging machine. A fitted shipping case, filled with stacks of box blanks and upper and lower inserts, has a plurality of holes in its upper and lower flaps for cooperating with an automated unloading machine. Inserts enclosed in the shipping case minimize damage due to shifting of the box blank stacks, provide added resistance against case failure during transit, and cooperate with the automated unloading machine to facilitate removal of the box blank stacks from the shipping case.

Shipping case and insert for automated box blank handling system

A system is provided for packing, shipping and automated unloading of stacks of box blanks so as to minimize damage to the box blanks and facilitate the insertion of the box blanks into an automated packaging machine. A fitted shipping case, filled with stacks of box blanks and upper and lower inserts, has a plurality of holes in its upper and lower flaps for cooperating with an automated unloading machine. The inserts enclosed in the shipping case minimize damage due to shifting of the box blank stacks, provide added resistance against case failure during transit, and cooperate with the automated unloading machine to faciltiate removal of the box blank stacks from the shipping case. The automated shipping case unloading machine features a stationary case gripping portion, an upper portion for opening the shipping case and removing the upper insert, and a plurality of carriage assemblies for lifting the stacks of box blanks out of the shipping case and conveniently presenting the stacks for further manual or automated handling.

Growing community of inventors

Midlothian, VA, United States of America

Gary E Grollimund