Other

University System of Maryland

Usbiomaterials Corporation

Gary David Hack

David C Greenspan

Leonard J Litkowski

Van Purdy Thompson

Joseph Anthony Von Fraunhofer

The present invention relates to methods and compositions for inhibiting, treating, and preventing dental diseases in human and non-human animals, particularly domesticated companion animals. More particularly, the present invention relates to the unexpected discovery that the combination of micron-sized particulate bioactive glass and a topical bisphosphonate yields a composition that is capable of treating and/or preventing dental problems such as periodontal disease, tooth decay and tooth resorption in animals, particularly small mammals such as cats.

Treatment and prevention of dental pathology in humans and non-human animals

Methods for whitening teeth including contacting teeth with an effective amount of particulate bioactive glass are disclosed.

Methods and compositions for whitening teeth

A novel silica based bioactive glass composition that can be used in conjunction with a delivery agent such as a toothpaste, gel saliva, etc. having a particle size range <90 &mgr;m which will form a rapid and continuous reaction with body fluids due to the immediate and long term ionic release of Ca and P from the core silica particles, to produce a stable crystalline hydroxy carbonate apatite layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity.

Compositions containing bioactive glass and their use in treating tooth hypersensitivity

A novel silica based bioactive glass composition that can be used in conjunction with a delivery agent such as a toothpaste, gel, etc. having a particle size range <90 &mgr;m which will form a rapid and continuous reaction with body fluids due to the immediate and long term ionic release of Ca and P from the core silica particles, to produce a stable crystalline hydroxy carbonate apatite layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.

Bioactive glass compositions and methods of treatment using bioactive glass

A novel silica based bioactive glass composition that can be used in conjunction with a delivery agent such as a toothpaste, gel, etc. having a particle size range &lt;90 .mu.gm which will form a rapid and continuous reaction with body fluids due to the immediate and long term ionic release of Ca and P from the core silica particles, to produce a stable crystalline hydroxy carbonate apatite layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.

Methods of treatment using bioactive glass

A highly acidic oxalate ion-containing preparation, which includes a neuroactive substance, for reducing tooth hypersensitivity, and a method for using same are disclosed.

One-step method and preparation for reducing dentinal hypersensitivity

A two-step method for treating tooth hypersensitivity so as to prevent, reduce or eliminate the same, and a kit for use in the same, are disclosed.

Method and kit for treating tooth hypersensitivity

A novel silica based bioactive glass composition that can be used in conjunction with a delivery agent such as a toothpaste, gel saliva, etc. having a particle size range &lt;90 .mu.m which will form a rapid and continuous reaction with body fluids due to the immediate and long term ionic release of Ca and P from the core silica particles, to produce a stable crystalline hydroxy carbonate apatite layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity.

Growing community of inventors

Columbia, MD, United States of America

Gary David Hack