Genzyme Corporation

Anormed, Inc.

Genzyme Global S.à.r.l.

Gary B Calandra

Gary James Bridger

Michael J Abrams

Geoffrey W Henson

Ronald Trevor MacFarland

Hal E Broxmeyer

David C Dale

Ronald Trevor Macfarland

C David Dale

Dale C David David

Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed. Preferred embodiments of such compounds are of the formulaZ-linker-Z'&#x2003;&#x2003;(1) 

Methods to mobilize progenitor/stem cells

Methods to elevate progenitor and stem cell counts in animal subjects using compounds which bind to the chemokine receptor CXCR4 are disclosed. Preferred embodiments of such compounds are of the formulaZ-linker-Z' &#x2003;&#x2003;(1) 

Certain nitrogen-containing compounds that bind the chemokine receptor CXCR4 are able to mobilize progenitor and/or stem cells into the peripheral blood to permit harvesting them for stem cell transplantation.

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Cresco, PA, United States of America

Gary B Calandra