Medivance, Inc.

Cobe Laboratories, Inc.

Sorin Group Usa, Inc.

Cobe Cardiovascular Operating Co., Inc.

Gary Allen Carson

Michael R Hoglund

Gary Gruszecki

Bruce S Ellingboe

Marc E Voorhees

Robert Proctor

Kerri Record

John J Kappus

James D Isaacson

Kevin J Kollar

Roger J Elgas

Robert E Doty

Bruce Ellingboe

William D Dalke

Rodger L Stewart

Mike E Schwab

Bruce E Lawrence

Axel Sjogren

Timothy Taga

J Steven Ingebrigtsen

Timothy M Gordon

Steve Whitehead

Steven Estergreen

Steve Estergreen

Gary Gruzecki

A patient temperature control system for automated temperature control according to a programmed protocol. In one aspect, at least one programmed protocol may be established for each of a plurality of patient thermal therapy phases. In turn, the temperature of a thermal exchange medium may be controlled upon the programmed protocol during each of the phases. A plurality of programmed protocols may be established, wherein a selected protocol may be utilized for automated temperature control during patient thermal therapy. The protocol may include a target patient temperature and/or a set duration for one or more of the phase of thermal therapy. The protocol may be user-definable and modifiable during therapy. In a multiphase configuration, automatic termination and initiation of successive phases may be selectively established by a user, based on target patient temperature data and/or set duration data on a phase-specific basis.

System and method for patient temperature control

A system and method are provided, the system including a monitoring device to monitor sensory data of a patient and to provide a sensory data response thereto, and a control unit configurable to cool or warm circulated fluid through at least one contact pad for thermal exchange with the patient. The monitoring device can be configured to monitor a patient physiological response to a change in temperature of the patient (e.g. pursuant to induced hypothermia therapy), wherein a monitoring signal is provided by the monitoring device. A processor can be provided to process the monitoring signal and provide an output employable by medical personnel. The processor can be programmed to control automatically a temperature of the circulated fluid to cool or warm the patient in different treatment phases in accordance with a predetermined protocol, and process the sensory data signal to provide an output signal indicative of a sensory measurement.

Patient temperature response control system and method

A patient temperature control system and method are provided for automated temperature control according to a programmed protocol. In one aspect, at least one programmed protocol may be established for each of a plurality of patient thermal therapy phases. In turn, the temperature of a thermal exchange medium may be controlled, based at least in part, upon the programmed protocol, during each of the phases. In another aspect, a plurality of programmed protocols may be established, wherein a selected one of the protocols (e.g. selected by a user at a user interface) may be utilized for automated temperature control during patient thermal therapy. The protocol(s) may include a target patient temperature and/or a set duration for one or more of the phase of thermal therapy. Further, the protocol(s) may be user-definable and modifiable during therapy. In a multi-phase configuration, automatic termination and initiation of successive phases may be selectively established by a user, based on target patient temperature data and/or set duration data on a phase-specific basis.

A system and method are provided that employ a monitoring device to monitor at least one patient physiological response to a change in temperature of the patient (e.g. pursuant to induced hypothermia therapy), wherein a monitoring signal is provided by the monitoring device. In turn, an output (e.g. a visual and/or auditory output) may be provided to a user indicative of at least one measure of patient response to the change in temperature. Alternatively or additionally, a processor may be provided to process the monitoring signal and provide an output employable by medical personnel to control a patient shivering response to the patient temperature change. Such information may comprise information regarding one or more anti-shivering medicament(s), e.g. corresponding dosage and/or frequency information for use by medical personnel in the administration of the anti-shivering medicament. In one approach, a motion sensor may be selectively attached to a patient's chin to provide a wireless monitoring signal to a transceiver. In turn, the transceiver may provide the monitoring signal to the processor on an ongoing basis to output information useful in the administration of an anti-shivering medicament, including updated information that takes into account a patient's response to a prior administration of one or more medicaments in conjunction with the subsequent administration of an anti-shivering medicament.

A sorption-based, adhesive contact apparatus and method for contact cooling a patient via conductive thermal exchange are described. The apparatus includes a pad, having a fluid containing layer and adhesive contact surface, and a sorption-based device, fluidly interconnectable to the fluid containing layer, for vaporizing fluid contained in the fluid containing layer and for sorping the vaporized fluid. The fluid vaporization and the vapor sorption cools the adhesive contact surface of the pad. A port control member may selectively establish fluid interconnection between the fluid containing layer and sorption-based device. An internal pressure of the sorption-based device may be established lower than an internal pressure of the fluid-containing layer prior to fluid interconnection therebetween. A fluid retention member and path defining members may be included to facilitate vaporization, vapor diffusion and vapor sorption, thereby enhancing uniform cooling.

Sorption-based adhesive contact cooling apparatus and method

A medical pad has multiple layers. A first layer is for containing a first thermal-exchange fluid circulatable therethrough, with the medical pad being operable for thermal exchange between the first thermal-exchange fluid and a patient through a first side of the first layer. A second layer of the medical pad is interconnected to a second side of the first layer, opposite to the first side of the first layer. The second layer encloses a second thermal-exchange fluid that may have a freezing point of 0&#xb0; C. or less. The medical pad is operable for thermal exchange between the second thermal-exchange fluid and the patient.

Cooling medical pad

An extracorporeal blood perfusion system includes a disposable assembly and a control unit having a control interface region. The interface region includes pump assemblies for selective pumping of venous blood, arterial blood, cardioplegia solution, suctioned blood and blood removed from the left ventricle. Valve assemblies control the flow of fluids through the assembly and to/from the patient and sensors monitor various fluid parameters including temperature and pressure within the various fluid circuits. The user interface is a functional screen interface for effecting the operation of the control unit and valve assemblies. The screen interface may be a touch screen having objects that corresponds to the component interface region. The display may be selectively controlled to provide graphic depictions of disposable assembly components with corresponding narrative instructions.

Blood perfusion system

A portable patient cooling apparatus is provided that includes a self-contained refrigerator and on-board power storage supply for stand alone operation. The apparatus is interconnectable to one or more heat exchange devices (e.g. patient contact pads or intravascular catheters) through which a cooled fluid may be circulated for patient cooling. Such fluid may be liquid contained within a reservoir comprising the apparatus during periods of non-use. The apparatus preferably defines a total volume of less than about 0.04 m, while having a total weight of less than about 15 kg to yield a total circulated fluid cooling capacity of at least 200 watts.

Portable, refrigerant-based apparatus and method for rapid systemic patient cooling

A portable apparatus and method for providing a cooled liquid for vascular administration are disclosed. The portable apparatus includes a source of liquid for vascular administration, a cooling reservoir for receiving liquid from the source, and a sorption-based heat exchanger for cooling liquid in the cooling reservoir by a sorption-based process. The heat exchanger may include an evaporative area for receiving and vaporizing a refrigerant, a sorptive material for sorping vaporized refrigerant, and a heat exchange member for conducting thermal energy from liquid in the cooling reservoir into the evaporative area. Additional componentry may be provided for fluidly interconnecting and controlling the flow of liquid from the source to the cooling reservoir and from the cooling reservoir to a vascular interface device. Such componentry may be conveniently packaged in a sterilized manner together with at least the cooling reservoir.

Apparatus and method for cooling liquid in intravascular cooling system

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Golden, CO, United States of America

Gary Allen Carson