Korea Electrotechnology Research Institute

Inthesmart Co., Ltd.

Garry V Papayan

Uk Kang

Guang Hoon Kim

Soo Jin Bae

Il Hyung Shin

Dae Sic Lee

Min Woong Jung

Vladimir Berezin

The present invention provides a transmitted light detection type measurement apparatus for skin fluorescence, which is configured to perform light irradiation and light detection on a reference sample and a measurement target. The apparatus includes a first light source, a second light source, a first optical detector and a second optical detector, a light source switching controller, and an operator.

Transmitted light detection type measurement apparatus for skin autofluorescence

Provided is a reflection detection type measurement method for skin fluorescence. The method includes: irradiating excitation light on a measurement target; detecting a reflected light and a skin fluorescence generated from the measurement target due to the excitation light; irradiating light with a wavelength range of the skin fluorescence on the measurement target; detecting a reflected light generated from the measurement target due to the light with a wavelength range of the skin fluorescence; and calculating a skin fluorescence value of the measurement target by correcting a calculation based on the detected reflected light and skin fluorescence.

Reflection detection type measurement apparatus and method for skin autofluorescence

The present invention relates to a filter switching device for a fluorescence endoscopic television camera system, and more particularly, to a filter switching device for a fluorescence endoscopic television camera system, which selectively transmits light to a detector sensor of a television camera according to the white light condition or the fluorescence condition to diagnose patients using a fluorescence endoscope. The present invention provides a filter switching device for a fluorescence endoscopic television camera system, which is configured to conveniently switch filters according to the rotational movement of the camera head, by inducing a change of magnetic forces according to the rotation of the camera head by magnetic substances disposed therein while maintaining a sealed structure inside the camera head connecting between a fluorescence endoscope and a television camera and thus allowing the frame of the camera head mounted with two types of filter to move upward and downward.

Filter switching device for fluorescence endoscopic television camera system

The present invention relates to a device for observing a sentinel lymph node (SLN) in a human body. More particularly, the present invention relates to a device for observing an SLN by detecting near-infrared (NIR) fluorescence caused by a fluorescent material such as indocyanine green (ICG) at the SLN and a method for detecting NIR fluorescence at an SLN. Particularly, in the implementation of a composite image obtained by reproducing a fluorescent material such as ICG and NIR fluorescence emitted by excitation light together with a visible light image, it is possible to detect an SLN with high accuracy through a color contrast method and/or a temporal modulation method using an NIR fluorescence image signal and a visible reflection light image signal.

Apparatus and method for detecting NIR fluorescence at sentinel lymph node

The present invention provides a reflection detection type measurement apparatus for skin fluorescence, which is configured to perform light irradiation and light detection on a reference sample and a measurement target.

Reflection detection type measurement apparatus for skin autofluorescence

Disclosed is an improved fluorescent endoscope system having reduced factors that cause errors during diagnosis based on quantitative evaluation of fluorescent intensity for improved accuracy of fluorescent endoscopic diagnosis. The fluorescent endoscope system includes an optical source module for providing white light or excitation light; an endoscope assembly having an optical transmission path for transmitting light provided from the optical source module to a diagnostic object and an optical detection module for transmitting reflection light and fluorescent light from the diagnostic object; an optical path split means for splitting the path of the reflection light and fluorescent light transmitted from the endoscope assembly; and a two-chip integration image detection module having a first optical detection chip for detecting the reflection light and outputting a first optical detection signal, a second optical detection chip for detecting the excitation light and outputting a second optical detection signal, a gain control unit for controlling a signal amplification gain value to adjust the brightness of an image detected by the first optical detection chip, a first amplification unit for amplifying the first optical detection signal according to the signal amplification gain value, and a second amplification unit for amplifying the second optical detection signal according to a changing ratio of the signal amplification gain value.

Fluorescent endoscope system having improved image detection module

The present invention relates, in general, to a fluorescence microscope and method of observing samples using the microscope and, more particularly, to a fluorescence microscope and method of observing samples using the microscope, which can reduce optical noise and obtain images with higher sensitivity, thus obtaining precise information about the density, quantity, location, etc. of a fluorophore, and which can simultaneously process separate images even when a plurality of fluorophores having different excitation and fluorescent wavelength ranges is distributed, thus easily obtaining information about the fluorophores. The fluorescence microscope of the present invention includes an objective lens, and first and third medium units. The first medium unit has a refractive index of nto accommodate one or more micro-objects including fluorophores and provide a path of excitation light to excite the fluorophores. The third medium unit has a refractive index of n, and is placed between the first medium unit and the objective lens to totally reflect the excitation light incident through the first medium unit at an interface of the third medium unit coming into contact with the first medium unit. The refractive indices of the third and first medium units satisfy a relationship of n&#x3e;n.

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St. Petersburg, Russia

Garry V Papayan