Johns Hopkins University

Garry R Cutting

Peter C Searson

Haig H Kazazian, Jr

Dong-Hoon Choi

Stylianos E Antonarakis

A potentiometric sensor that includes a housing and working electrode is provided. The housing includes a reference electrode, a first hydrogel containing hydrogel that contains a reference solution, and a salt bridge. The sensor is wearable and can be used for continuous on-body sweat measurements.

Potentiometric wearable sweat sensor

Four mutations have been found clustered in exon 11 of the CFTR (cystic fibrosis transmembrane conductance regulator) gene. These mutations occur within a set of amino acids highly conserved among ATP-dependent transport proteins. Humans can be tested to determine whether they carry one of these mutations using a number of methods and/or probes taught herein. Specifically the mutations include: Asn.sub.549, Asp.sub.551, Stop.sub.553, and Thr.sub.559.

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Baltimore, MD, United States of America

Garry R Cutting