Leland Stanford Junior University

University of Illinois

Garry Chinn

Craig Steven Levin

Peter D Olcott

Ewout Van Den Berg

Emmanuel J Candes

Shiva Abbaszadeh

Carlos Alberto Sing-Long Collao

Angela M Foudray

Measuring in a first semiconductor crystal two anode channels and two cathode channels and measuring in a second semiconductor crystal one anode channel and one cathode channel; responsive to an energy of a sum of the two anode channels being within an energy window and an energy of the one anode channel being within the energy window: separating the two anode channels and the two cathode channels into combinations of anode-cathode channel pairs; for each of the anode-cathode channel pairs, determining a respective direction difference angle, each respective direction difference angle being determined via use of the one anode channel and one cathode channel; determining a determined one of the direction difference angles that has a smallest value; and setting as an initial interaction position of a photon a selected one of the anode-cathode channel pairs that corresponds to the determined direction difference angle. Additional embodiments are disclosed.

Method and system for increasing radiation sensitivity in semiconductor detectors

A method for providing an image from a device with a plurality of sensors and a plurality of time to digital converters (TDC) is provided. Data signals are generated by some of the plurality of sensors, wherein each sensor of the plurality of sensors provides output in parallel to more than one TDC of the plurality of TDCs and wherein each TDC of the plurality of TDCs receives in parallel input from more than one sensor of the plurality of sensors and where a binary matrix indicates which sensors are connected to which TDC. The data signals are transmitted from the sensors to the TDCs. TDC signals are generated from the data signals. Group testing is used to decode the TDC signals based on the binary matrix.

Digital multiplexing readout for sparse signals on imaging arrays

Compressed sensing (CS) estimation approaches rely on a priori sparsity to significantly reduce the number of samples needed to provide high sampling fidelity, relative to the normal Shannon-Nyquist limit. Accordingly, CS approaches are of considerable interest for detector multiplexing in applications which have inherently sparse signals (e.g., the two correlated photon detection events in PET imaging). However, CS approaches also tend to fare poorly in the presence of noise, which has limited their applicability in practice. In this work, we show that CS estimation can be used to provide an estimate of the support of an image. This estimated support is then used as a constraint for maximum likelihood image reconstruction. This approach has robust noise performance and provides high reconstruction fidelity.

Noise robust decoder for multiplexing readout channels on an imaging sensor array

Methods and systems for producing an image. Measurement data is obtained for a coincidence photon event, and a line projector function is generated based on the obtained measurement data. Additional measurement data is obtained for a single photon event, and a cone-surface projector function is generated based on the additional measurement data. An image is reconstructed using the generated line projector function and the generated cone-surface projector function. In another example method for producing an image, a measurement is obtained, and a projector function is generated using the obtained measurement. The generated projector function is modified based on an a priori image. An image is reconstructed using the modified projector function.

System and method for tomography combining single and paired photons

Methods and systems for producing an image. A measurement is obtained, and a projector function is generated using the obtained measurement. The generated projector function is modified based on an a priori image. An image is reconstructed using the modified projector function.

System and method for using multiple collimation data for tomography

Methods and systems for determining a location of a photon event for an imaging system including a plurality of 3-D detectors. For one of the photons in the photon pair, an interaction in a first 3-D detector is detected. For the other of the photons in the photon pair, at least two interactions in a second 3-D detector are detected. A cone-surface projector function is produced based on the at least two interaction locations in the second 3-D detector. A projector function is produced based on the produced cone-surface projector function, the detected interaction in the first 3-D detector, and the at least two detected interactions in the second 3-D detector.

Growing community of inventors

San Mateo, CA, United States of America

Garry Chinn