Nanalysis Corp.

Garett M Leskowitz

Neal Gallagher

Adam Paulson

Colten Wright

Kent Davidson

Jean-Sebastien Langlois

Andre Huard

Christian Gauvin

Sebastien Larose

Gregory McFeetors

Susanne D Riegel

Mark Elliott

Stephane Sanschagrin

Sebastien Pernecker

A pole piece for use in a Halbach-type magnet configuration, the pole piece having an elongated body adapted for insertion into the Halbach-type magnet configuration and having at least two parts operably and removably connected to each other. The at least two parts of the pole piece comprise a top iron having a front face and a rear face, a bottom iron having a front face and a rear face, and an interstitial shim layer adapted to be inserted in a shim cavity defined by a depression formed in at least one of: the front face of the top iron and the rear face of the bottom iron. A method for shimming includes modifying a material content of the shim cavity and inserting the pole piece into the central cavity of the Halbach-type magnet configuration for shimming the magnetic field generated.

Pole piece

The present document describes methods and systems for exciting magnetic resonance in a sample using trains of pulsed, oscillating magnetic fields that are modulated in their phase and amplitude according to a source waveform derived from the known or estimated magnetic response of a sample. Also disclosed are methods and systems for acquiring a response signal from the sample wherein data acquisition events are synchronized or interleaved with said modulated pulse trains. Further disclosed are methods and systems for identifying one or more of the presence, absence, amount, and concentration of a target substance in a sample. Also disclosed is a magnetic resonance device which uses such pulse trains and synchronized acquisition to improve the selectivity of magnetic resonance data.

Methods and systems for acquiring magnetic resonance data from a sample

A magnet array is disclosed comprising a plurality of polyhedral magnets arranged in a Halbach cylinder configuration, the centers of individual ones of the plurality of polyhedral magnets being arranged substantially in a plane in a magnet rack, the plurality of the polyhedral magnets at least partly enclosing a testing volume, and comprising a first plurality of polyhedral magnets arranged in a Halbach cylinder configuration and a second plurality of polyhedral magnets arranged in a non-Halbach configuration. In another aspect, a magnet array is disclosed comprising a first subset and a second subset of polyhedral magnets having different coercivities. In yet another aspect, a magnet array is disclosed wherein a subset of the centers of the individual ones of the plurality of polyhedral magnets are laterally displaced from a nominal position in the magnet rack to counteract a magnetic field gradient of the magnet array.

Magnet configurations

NMR spectrometer

NMR spectrometer with adjustable display

There are disclosed magnet arrays and methods for generating magnetic fields. In embodiments magnet arrays comprise a plurality of polyhedral magnets arranged in a lattice configuration and at least partly enclosing a testing volume, the magnet array having an associated magnetic field with a designated field direction {circumflex over (v)}, wherein the magnetization direction {circumflex over (m)} of an individual polyhedral magnet located at a displacement vector {right arrow over (r)} from an origin point in the testing volume is determined by the formula: {circumflex over (m)}=(2({circumflex over (v)}&#xb7;{right arrow over (r)}){right arrow over (r)}&#x2212;({right arrow over (r)}&#xb7;{right arrow over (r)}){circumflex over (v)})/{right arrow over (r)}&#xb7;{right arrow over (r)}. In embodiments the arrays are comprised in magnetic resonance machines. In embodiments the polyhedral magnets are truncated cubes or are rhombic dodecahedra.

Lattice configurations of polyhedral component magnets

There are disclosed pole piece designs. In embodiments a pole piece comprises a rear face, the rear face comprising at least one channel. In embodiments the pole piece comprises at least one hole for accepting a cooperating shimming rod. There are also disclosed magnet arrays and magnetic resonance apparatuses comprising the pole pieces as well as uses of the pole pieces with magnet arrays according to embodiments.

A method for shimming a magnetic field is disclosed. The method uses a single shim current to contribute to suppression of more than one geometrical component of an inhomogeneity in the magnetic field without changing the geometry of the shim path. Apparatuses to implement the method are also disclosed. In embodiments the apparatuses comprise substantially commonly oriented shim paths.

Growing community of inventors

Calgary, Canada

Garett M Leskowitz