Merck Sharp + Dohme Corp.

Chinese Academy of Sciences

Beijing Baidu Netcom Science Technology Co., Ltd

Gang Ji

Jianmin Fu

Subharekha Raghavan

Alan Whitehead

Joie Garfunkle

Raphaelle Berger

Falong Jiang

Yong Zhang

Guoqing Li

Cameron James Smith

Shouwu Miao

Yi-Heng Chen

John E Stelmach

Rui Zhang

Hong-Dong Li

Chao Tian

Lei Jia

Hong Li

Zhiqiang Yang

Olga Ornoski

Fei Sun

Shuoguo Li

Raphelle Berger

John Stelmach

A task processing method, an electronic device and a storage medium, which relate to the field of artificial intelligence, such as intelligent voices, artificial intelligence chips, or the like, are disclosed. The method may include: for to-be-executed tasks, in at least one round of processing, performing the following operations: in response to determining that one or more high-priority tasks exist in the to-be-executed tasks, calling the one or more high-priority tasks to process audio data cached in a memory; and after execution of the one or more high-priority tasks is completed, and in response to determining that one or more low-priority task exist in the to-be-executed tasks, calling the one or more low-priority tasks to process the audio data.

Task processing method and apparatus, electronic device and storage medium

The invention provides certain fused pyrazine compounds of the Formula (I) or a pharmaceutically acceptable salts thereof, wherein X, Y, R, R, R, R, R, R, and the subscript t are as described herein. The compounds or their pharmaceutically acceptable salts can modulate the body's production of cyclic guanosine monophosphate ('cGMP'), and are generally suitable for the therapy and prophylaxis of diseases or disorders which are associated with a disturbed cGMP balance. The invention also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The invention also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of the abovementioned diseases and disorders and for preparing pharmaceuticals for this purpose. 

Fused pyrazine derivatives useful as soluble guanylate cyclase stimulators

The invention provides compounds of the Formula (I) or a pharmaceutically acceptable salts thereof, wherein X, Y, Z, R, R, R, R, and the subscripts m, p, and q are as described herein. The compounds or their pharmaceutically acceptable salts can modulate the body's production of cyclic guanosine monophosphate ('cGMP'), and are generally suitable for the therapy and prophylaxis of diseases which are associated with a disturbed cGMP balance. The invention also provides pharmaceutical compositions which comprise compounds of Formula (I) or pharmaceutically acceptable salts thereof. The invention also relates to methods for use of the compounds or their pharmaceutically acceptable salts in the therapy and prophylaxis of the abovementioned diseases and for preparing pharmaceuticals for this purpose.

Soluble guanylate cyclase stimulators

An optical vacuum cryostage for correlative light and electron microscopy comprises a vacuum chamber, an anti-contamination system adapter interface, an electron microscope specimen holder adapter interface, an upper optical window, a lower optical window, a vacuum pumping system adapter interface and a vacuum valve, wherein the anti-contamination system adapter interface is arranged in one end of the vacuum chamber, the electron microscope specimen holder adapter interface is arranged in the other end of the vacuum chamber, the upper optical window is arranged on the upper wall of the vacuum chamber, the lower optical window is arranged on the lower wall of the vacuum chamber and opposite to the upper optical window.

Optical vacuum cryo-stage for correlative light and electron microscopy

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Beijing, China

Gang Ji