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Vsesojuny Kardiologichesky Nauchny Tsentr Adkaemii Meditsinski Nauk Sssr

Vsesojuzny Nauchno-issledovatelsky I Ispytateiny Institut Meditsinskoi

Vsesojuzny Kardiologichesky Nauchny Tsentr Akademii Meditsinskiki Nauk

Galina A Gerasimova

Anatoly B Davydov

Rustam I Utyamyshev

Gennady L Khromov

Eduard A Babaian

Vladimir I Metelitsa

Konstantin L Savvateev

Elizaveta B Novikova

Anatoly M Vikhert

Vladimir K Piotrovsky

An antianginal composition in the form of a plate is provided for treating ischemic heart disease and is comprised of a biologically soluble and resolvable film and an antianginal coronary vasodilating nitrate. This film is placed buccally on the gum or mouth mucosa for rapid arresting or prevention of angina pectoris attacks. The antianginal film is in the form of a plate, 0.1 to 1.5 mm thick, consisting of a biologically soluble and resolvable carrier. Preferably, the film is comprised of a homoploymer of acrylamide or vinylpyrrolidone, or a copolymer thereof with acrylate, containing from 99 to 70 percent by weight of acrylamide with vinylpyrrolidone and from 1 to 30 percent by weight of acrylate having a molecular mass from 50,000 to 1,000,000, and the active principle having antianginal action, the components being taken in the following proportions, in percent by weight:

Antianginal plate for treating ischemic heart disease

An antianginal composition in the form of a plate is provided for treating ischemic heart disease and is comprised of a biologically soluble and resolvable film and an antianginal coronary vasodilating nitrate. This film is placed buccally on the gum or mouth mucosa for rapid arresting or prevention of angina pectoris attacks. The antianginal film is in the form of a plate, 0.1 to 1.5 mm thick, consisting of a biologically soluble and resolvable carrier. Preferably, the film is comprised of a homopolymer of acrylamide or vinylpyrrolidone, or a copolymer thereof with acrylate, containing from 99 to 70 percent by weight of acrylamide with vinylpyrrolidone and from 1 to 30 percent by weight of acrylate having a molecular mass from 50,000 to 1,000,000 and the active principle having antianginal action, the components being taken in the following proportions, in percent by weight:

The antianginal film is a plate, 0.1 to 1.5 thick, consisting of a biologically soluble and resolvable carrier, which is a hompolymer of acrylamide or vinylpyrrolidone, or a copolymer thereof with acrylate, containing from 99 to 70 percent by weight of acrylamide with vinylpyrrolidone and from 1 to 30 percent by weight of acrylate having a molecular mass from 50,000 to 1,000,000, and the active principle having antianginal action, the components being taken in the following proportions, in percent by weight:

Antianginal film and method of treating ischemic heart disease

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Moscow, Russia

Galina A Gerasimova