Tel Hashomer Medical Research Infrastructure and Services Ltd.

Ministry of Health, State of Israel

Sami Shamoon College of Engineering (r.a.)

Sami Shamoon College of Engineeing (r.a)

Sami Shamoon College of Engineering

Galia Rahav

Yoram Shotland

Yakov Davidov

Chaim Rubinovitz

Ari Robinson

Noa Lea Tejman-yarden

Noa Lea Tejman-Yarden

Israel Nissan

Ohad Gal-Mor

Cultures ofbacteria are disclosed. Antimicrobial agents derived therefrom are also disclosed.

Antimicrobial compounds from the genus

Cultures of Delftia bacteria are disclosed. Antimicrobial agents derived therefrom are also disclosed.

Methods of inhibiting bacterial conjugation, bacterial horizontal gene transfer or bacterial growth are disclosed. The methods comprise contacting bacteria with an effective amount of a bile acid or a bile salt, wherein the effective amount does not affect viability of the bacteria. A method of increasing susceptibility of bacteria to antibiotic treatment is also disclosed as well as methods of decontaminating a farm animal housing or a medical surface and methods of treating water. Also disclosed are compositions effective in inhibiting bacterial conjugation, bacterial horizontal gene transfer and bacterial growth.

Use of bile acids and bile salts as anti bacterial agents for inhibition of bacterial conjugation and horizontal gene transfer

Growing community of inventors

Jerusalem, Israel

Galia Rahav