Other

Bar-Ilan University

Ariel Scientific Innovations Ltd.

Gal Yadid

Rachela Popovtzer

Eugene O Major

Malka Cohen-Armon

Carlo S Tornatore

Elad Lax

Michael Firer

Joseph Zohar

Peptides effective as delta opioid receptor agonists and compositions comprising same are provided. Further provided are methods for targeting medical conditions amenable to treatment with an opioid receptor agonist, including but not limited to, conditions involving pain as well as reducing cocaine craving.

Delta receptor agonist peptides and use thereof

The invention discloses methods for preventing or treating addiction by administering to a subject in need thereof a PARP inhibitor.

Treatment of addiction

The invention relates to production of maladapted animals characterized by PTSD like behavior from a population by behavioral conditioning. The method includes determining a baseline behavioral level for individual under defined conditions; exposing each individual animal to trauma event and further determining a posttraumatic event behavioral level; re-exposing each individual to a trauma related event and further determining an individual post trauma related event behavioral level and evaluating the individual post trauma related event behavioral level for each individual animal with respect to a baseline value according to a predetermined rule in order to determine which individuals are maladapted animals characterized by PTSD like behavior. Use of the method for assaying efficacy of PTSD treatment is within the scope of the invention, as are animals produced by claimed methods. Once the method is established, biological parameters may be employed in addition to, or in lieu of behavioral parameters.

Nonhuman mammals exhibiting PTSD-like behavior

The present invention generally relates to methods for treating a host by implanting genetically unrelated cells in the host. More particularly, the present invention provides human fetal neuro-derived cell lines, and methods of treating a host by implantation of these immortalized human fetal neuro-derived cells into the host.

Growing community of inventors

Shoham, Israel

Gal Yadid