Covidien LP

Nellcor Puritan Bennett Incorporated

Gail Frances Upham

Mehdi Matthew Jafari

Rhomere S Jimenez

Jeffrey K Aviano

Peter Doyle

Warren G Sanborn

Gardner Kimm

Gary Milne

Edward R McCoy

Michael K Davis

Richard Nakai

Mahesh K Seetharaman

Cynthia Miller

David Luis Figueiredo

Medhi M Jafari

Daniel G Grabol

Edward Mccoy

This disclosure describes systems and methods for providing drive pressure ventilation of a patient. The disclosure describes a novel breath type that provides a spontaneous breath type that allows for the calculation of drive pressure that does not require invasive monitoring.

Systems and methods for drive pressure spontaneous ventilation

This disclosure describes systems and methods for compensating for leaks in a ventilation system based on data obtained during periods within a breath in which the patient is neither inhaling nor exhaling. The methods and systems described herein more accurately and quickly identify changes in leakage. This information is then to estimate leakage later in the same breath or in subsequent breaths to calculate a more accurate estimate of instantaneous leakage based on current conditions. The estimated leakage is then used to compensate for the leak flow rates, reduce the patient's work of breathing and increase the patient's comfort (patient-ventilator breath phase transition synchrony).

System and method for determining ventilator leakage during stable periods within a breath

This disclosure describes systems and methods for providing drive pressure ventilation of a patient. The disclosure describes a novel breath type that provides a spontaneous breath type that allows for the calculation of drive pressure that does not require invasive monitoring, where drive pressure is the pressure applied to the lungs that causes them to inflate during mechanical ventilation.

Systems and methods for compensating for leaks in a ventilation system based on data obtained during periods within a breath in which the patient is neither inhaling nor exhaling. The methods and systems described herein more accurately and quickly identify changes in leakage. This information is then to estimate leakage later in the same breath or in subsequent breaths to calculate a more accurate estimate of instantaneous leakage based on current conditions. The estimated leakage is then used to compensate for the leak flow rates, reduce the patient's work of breathing and increase the patient's comfort (patient-ventilator breath phase transition synchrony).

This disclosure describes systems and methods for detecting and quantifying transmission delays associated with distributed sensing and monitoring functions within a ventilatory system. Specifically, the present methods and systems described herein define an event-based delay detection algorithm for determining transmission delays between distributed signal measurement and processing subsystems and a central platform that receives data from these subsystems. It is important to evaluate and quantify transmission delays because dyssynchrony in data communication may result in the misalignment of visualization and monitoring systems or instability in closed-loop control systems. Generally, embodiments described herein seek to quantify transmission delays by selecting a ventilator-based defining event as a temporal baseline and calculating the delay between the inception of the defining event and the receipt of data regarding the defining event from one or more distributed sensing devices.

Event-based delay detection and control of networked systems in medical ventilation

This disclosure describes systems and methods for compensating for leakage when during delivery of gas from a medical ventilator in a proportional assist mode to a patient. The technology described herein includes systems and methods to compensate the delivery of PA ventilation for leakage in the patient circuit by using leak-compensated lung flows as well as leak-compensated respiratory mechanics parameters (lung compliance and lung resistance) estimated in a manner that compensates for elastic and inelastic leaks from the ventilation system.

Leak-compensated proportional assist ventilation

This disclosure describes systems and methods for compensating for leakage when during delivery of gas to a patient from a medical ventilator in a pressure regulated volume control (PRVC) ventilation mode. The technology described herein includes systems and methods that compensate the delivery of PRVC ventilation for leakage in the patient circuit by using leak-compensated lung flows as well as respiratory mechanics (lung compliance and lung resistance) estimated in a manner that compensates for elastic and inelastic leaks from the ventilation system.

Leak-compensated pressure regulated volume control ventilation

This disclosure describes systems and methods for detecting disconnect conditions in a ventilator. The disclosure describes a model-based enhancement to conventional disconnect detection. The methods and systems described herein compensate for the additional leakage that occurs due to inelastic and elastic leaks in the ventilation system. One method described includes calculating the actual leakage from the ventilation system including leaks from elastic leakage and inelastic leakage based on measurements of pressure and flow in the ventilation system for a breath and then comparing this leakage to a calculated hypothetical maximum allowable leakage determined based on an operator-selected maximum allowable leakage and the measurements of pressure for the same breath. Disconnection is assumed if the actual leakage is greater than the maximum allowable leakage.

Determination of patient circuit disconnect in leak-compensated ventilatory support

This disclosure describes systems and methods for purging narrow diameter sensor tubing, occasionally referred to as 'sensor lines,' in a ventilation system. The disclosure describes a novel approach in which a series of short, periodic releases of pressurized gas through the sensor tubes are used to clear any blockages due to condensation or patient secretions.

Inverse sawtooth pressure wave train purging in medical ventilators

An apparatus configured to display a three-dimensional representation of a waveform for a breathing assistance system may include a processor and a display device. The processor may be configured to receive signals from one or more sensors over a plurality of time periods and generate multiple instances of a waveform based on the received signals, each instance corresponding to one of the plurality of time periods. The display device may be configured to cooperate with the processor to display a graphical three-dimensional representation of the waveform over time. The three-dimensional representation may include graphical representations of the multiple instances of the waveform displayed simultaneously.

Three-dimensional waveform display for a breathing assistance system

This disclosure describes systems and methods for compensating for leakage when determining the respiratory mechanics of a patient during delivery of gas from a medical ventilator to a patient. The systems and methods include monitoring an instantaneous flow in the ventilation system based on one or more measurements of pressure and flow in ventilation system. The leakage is modeled using a predetermined leakage model. A leak-compensated instantaneous lung flow of gas inhaled or exhaled by the patient is estimated. Using the leak-compensated lung flow and a predetermined respiratory mechanics model, the respiratory mechanics of a patient may be estimated including at least one of a leak-compensated lung compliance and a leak-compensated lung resistance. The method may include using a dynamic respiratory mechanics model or a static respiratory mechanics model that requires use of a pause maneuver to collect the necessary data.

Leak-compensated respiratory mechanics estimation in medical ventilators

This disclosure describes systems and methods for compensating for inelastic and elastic leaks in a ventilation system. The disclosure describes a model-based enhancement to conventional flow triggering and cycling methodologies that improves the timing and patient work of flow-based triggering and cycling performance. The methods and systems described herein compensate for the leak condition and minimize additional effort a patient has to exert to generate the same patient synchrony and comfort level compared to no leak condition. One method described includes calculating an elastic leakage and an inelastic leakage based on current measurements of pressure and flow in the ventilation system and then estimating a leak-compensated lung flow using the inelastic and elastic leaks and pneumatic attributes of the patient-ventilator system.

Leak-compensated flow triggering and cycling in medical ventilators

This disclosure describes systems and methods for compensating for inelastic and elastic leaks in a ventilation system. The disclosure describes a model-based enhancement to conventional pressure triggering methodology that optimizes the timing and patient work of pressure triggering performance. The methods and systems described herein compensate for the additional effort a patient has to exert to generate the same amount of airway pressure drops compared to no leak condition. One method described includes calculating an elastic leakage and an inelastic leakage based on current measurements of pressure and flow in the ventilation system and then compensating a pressure threshold for the effects of the inelastic and elastic leaks in the system.

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Fallbrook, CA, United States of America

Gail Frances Upham