Bayer Aktiengesellschaft

The Hong Kong University of Science and Technology

Gabriele Schmuck

Arnd Voerste

Gisela Greif

Richard K Haynes

Ho-Wai Chan

Hing-Wo Tsang

Man-Ki Cheung

William Wai-Lun Lam

Uwe Petersen

Axel Dalhoff

Elmar Vilsmaier

Gunther Milch

Torsten Goerz

This invention relates to the use of certain C-10 substituted derivatives of artemisinin of general formula (I) in the treatment and/or prophylaxis of diseases caused by infection with a parasite, certain novel C-10 substituted derivatives of artemisinin, processes for their preparation and pharmaceutical compositions containing such C-10 substituted derivatives. The compounds are particularly effective in the treatment of malaria, neosporosis and coccidiosis. 

Antiparasitic artemisinin derivatives (endoperoxides)

This invention relates to the use of certain C-10 substituted derivatives of artemisinin of general formula (I) in the treatment and/or prophylaxis of diseases caused by infection with a parasite, certain novel C-10 substitued derivatives of artemisinin, processes for their preparation and pharmaceutical compositions containing such C-10 substituted derivatives. The compounds are particularly effective in the treatment of malaria, neosporosis and coccidiosis. 

This invention relates to the use of certain C-10 substituted derivatives of artemisinin of general formula (I) in the treatment and/or prophylaxis of diseases caused by infection with a parasite, certain novel C-10 substituted deriviatives of artemisinin, processes for their preparation and pharmaceutical compositions containing such C-10 substituted derivatives. The compounds are particularly effective in the treatment of malaria, neosporosis and coccidiosis.

6-Amino-3-azabicyclo&lsqb;3.1.0&rsqb;hexanes of the formula

Special 3-azabicyclo&lsqb;3.1.0&rsqb;hexanes, method for producing and modifying the same, and their use

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Wuppertal, Germany

Gabriele Schmuck