Evotec Technologies Gmbh

Perkinelmer Cellular Technologies Germany Gmbh

Evotec Biosystems Ag

Gabriele Gradl

Thomas Schnelle

G&uuml;nter Fuhr

Torsten M&uuml;ller

Rolf Hagedorn

Torsten Müller

Christoph Reichle

Stephen Graham Shirley

A method is described for non-destructive measurement of vitality of biological cells, especially for determination of apoptosis, in which the at least one cell is exposed to high-frequency alternating, especially rotating, electric fields and/or impedance test fields, and at least one rotation measurement, one dielectrophoresis measurement and/or one impedance measurement is performed with the cell for at least one frequency range or individual frequencies, from which at least one measurement parameter is determined that is characteristic of the vitality state of the cell.

Method for measuring the vitality of cells

A method for the prevention of the adhesion of particles, in particular cells and cellular components in solution to surfaces, characterized in that to the solution is added at least one polyalcohol.

Method for preventing the adhesion of particles

To manipulate microparticles in a fluid that intersects a first channel or several first channels as a stream, one or more microparticles ( ) are exposed to electrical field barriers that change their direction from the direction of flow toward the edge of the flow to a lateral hole ( ) of the respective first channel. As a result, microparticles can be moved back and forth between streaming fluids. Preferred applications include treatment, separating, sorting or confinement procedures.

Method and device for manipulating microparticles in fluid flows

An electroporation and/or fusion treatment of microscopic objects occurs in a medium between at least two electrodes, with the electrodes being miniaturized electrodes in a microsystem with a channel structure which is set up for the flow-through of the medium with the objects.

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Berlin, Germany

Gabriele Gradl