Rodan & Fields, LLC

Gabriele Di Fiore

Christine Marie Crane

George Paul Majewski

Dzung Q Le

Robert Bianchini

Olga Dueva-Koganov

John Simon Craw

Angela M Rivera

The compositions of various embodiments include a tocopherol phosphate mixture (TPM) comprising a liposome having a lipid bilayer and an internal aqueous compartment, a lipophilic ingredient, a polar solvent system, an alcohol, a base, and a water soluble phase, wherein the liposome is made of a tocopherol phosphate derivative, wherein the lipophilic ingredients are entrapped in the lipophilic bilayer of the liposome, and wherein a water soluble ingredient is dissolved in the water soluble phase and is in the internal compartment of the liposome. The methods include improving the look of skin particularly of the neck and décolletage, increasing expression of an extracellular matrix proteins in skin, improving a keloid scar in a subject, and improving aging skin. Additionally, methods for preparing the compositions are described herein.

Cosmetic compositions

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San Francisco, CA, United States of America

Gabriele Di Fiore