Societe Des Produits Nestle S.a.

Nestec S.a.

Gabriela Bergonzelli Degonda

Florence Rochat

Clara Lucia Garcia-Rodenas

Stephen Michael Collins

Elena Verdu De Bercik

Premysl Bercik

Peter McLean

Annick Mercenier

Stephane Duboux

Elizabeth Offord Cavin

Jeroen Antonius Johannes Schmitt

Isabelle Bureau-Franz

Christine Cherbut

Lisa Lamothe

Valerie Marquardt

Tiago Alves Nunes

François-Pierre Martin

Euridice Castaneda Gutierrez

Stephanie Viguet-Carrin

Kurt Ornstein

Muzi Tangyu

Lukas Van Oudenhove

Kristin Verbeke

Ornella Cominetti Allende

Stéphanie Viguet-Carrin

The present invention generally relates to the field of probiotic bacteria. In particular, it relates to methods for treating or preventing functional GI disorders comprising administering, such asATCC BAA-999.

and functional GI disorders

Use of a sugar selected from lactose, fructose and raffinose, for increasing serpin expression instrain CNCM I-2618.

Serpin production

Compositions and methods useNCC3001 (ATCC BAA-999) to treat or prevent a depressive symptom. Prolonged anti-depressive effects can continue after administration of the compositions is ended. Non-limiting examples of a depressive symptom which can be treated or prevented include depressed mood; sadness; anxiety; 'empty' feelings; loss of interest or pleasure; irritability; restlessness; changes in appetite or weight; sleep disturbances; lack of or decreased energy; feelings of worthlessness; guilt; helplessness; anger and hostility; difficulty in thinking, concentrating, or making decisions; hopelessness; tiredness; fatigue; memory difficulties; tearfulness; brooding; phobias; excessive worry over physical health; sexual dysfunction; persistent physical symptoms that do not respond to treatment; and combinations thereof. These depressive symptoms can be associated with a depressive state or depressive disorder or can be found sub-clinically or not associated with these depressive states/disorders (e.g., not part of a syndrome or psychiatric disorder).

Method of using bifidobacterium longum to treat depressive symptoms

The invention discloses a composition comprising at least one long chain polyunsaturated fatty acid, at least one probiotic and a mixture of oligosaccharides, said mixture containing at least one N-acetylated oligosaccharide, at least one sialylated oligosaccharide and at least one neutral oligosaccharide, for use in the promotion of healthy bone growth and/or in the prevention and/or treatment of bone disease. Said bone disease is in particular osteomalacia, rickets, osteopenia or osteoporosis. Preferably the composition is a nutritional composition.

Composition for use in the promotion of healthy bone growth and/or in the treatment of bone disease

This invention relates to the use of a probiotic bacterial strain in the manufacture of a medicament or therapeutic nutritional composition for improving the maturation of sleep patterns in infants, young children or young animals and/or for reducing sleep disturbances and/or improving sleep patterns in humans or animals at any age.

Nutritional composition comprising probiotics and improving sleep patterns

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Bussigny, Switzerland

Gabriela Bergonzelli Degonda