University of California

Gabriel M Rodriguez

Shota Atsumi

Yohei Tashiro

Justin Bloomfield Siegel

Michael D Toney

D Alexander Carlin

Irina Koryakina

Shuchi H Desai

The present disclosure provides recombinant bacteria with elevated production of ethanol and/or n-butanol from ethylene. Methods for the production of the recombinant bacteria, as well as for use thereof for production of ethanol and/or n-butanol are also provided.

Bacteria engineered for conversion of ethylene to ethanol

The present disclosure provides recombinant bacteria with elevated 2-keto acid decarboxylase and alcohol transferase activities. Some recombinant bacteria further have elevated aldehyde dehydrogenase activity. Some recombinant bacteria further have reduced alcohol dehydrogenase and/or aldehyde reductase activity. Methods for the production of the recombinant bacteria, as well as for use thereof for production of various esters are also provided.

Bacteria engineered for ester production

The present disclosure provides recombinantand other bacteria with reduced alcohol dehydrogenase and/or aldehyde reductase activity. The present disclosure further provides recombinantand other bacteria with reduced isobutyraldehyde reductase activity. Methods for the production and the uses of the recombinant bacteria are also provided. Specifically, recombinant bacteria further expressing 2-keto-acid decarboxylase can be used for producing higher aldehydes or other non-alcohol chemicals derived from aldehydes.

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Growing community of inventors

Davis, CA, United States of America

Gabriel M Rodriguez