Metabolys

Gabriel Baverel

Gérard Moinet

Remi Nazaret

Bernard Ferrier

Rémi Nazaret

Gerard Moinet

Compounds of formula (I) or their enantiomers, diastereoisomers thereof and the addition salts thereof with pharmaceutically acceptable bases or acids, for use for the prevention or treatment, preferably treatment, of NASH. 

Treatment for the non alcoholic steatohepatitis and fibrosis

The present disclosure relates to a composition including, in combination, metformin or a salt thereof, a pharmaceutically acceptable carrier or excipient and at least one compound of formula (I), or the enantiomers, diastereoisomers or pharmaceutically acceptable salts thereof. Formula (I) is as follows:  The present disclosure also relates to the use of this composition for the treatment of diseases associated with insulin resistance syndrome.

Composition and kit comprising piperazine derivatives and metformin, and use thereof in the treatment of diabetes

Disclosed herein are compounds and compositions useful in the treatment of pathologies associated with the insulin resistance syndrome (or syndrome X), in particular in the treatment of type 2 diabetes. 

Piperazine derivatives, methods for preparing same, and uses thereof in the treatment of insulin resistance

The invention relates to a compound of formula (I), where R, R, R, m, n, and Lare as defined in claim, and to the methods for preparing same, to the pharmaceutical compositions containing same, and to the uses thereof in the treatment of diseases associated with insulin resistance syndrome. 

Growing community of inventors

Saint Cyr au Mont d'or, France

Gabriel Baverel