Egis Gyogyszergyar

Schering Aktiengesellschaft

Richter Gedeon Vegyeszeti Gyar Rt

Egis Gyogyszergyar Rt.

Gis Gyogyszergyar Rt.

Gabor Zolyomi

Tamas Hamori

Ferenc Andrasi

Imre Moravcsik

Pal Berzsenyi

Jeno Korosi

Istvan Elekes

Tibor Lang

Peter Botka

Zsuzsanna Lang Nee Rihmer

Istvan Gyertyan

Jozsef Reiter

Gyorgy Rabloczky

Pal Vago

Istvan Ling

Maria Kuhar Nee Kurthy

Eszter Szentkuti

Katalin Horvath

Anna Bakonyi

Gyorgyne Mate

Tibor Hasko

Edit Horvath

Laszlo Szporny

Gyula Simig

Elemer Ezer

Antal Simay

Gabor Gigler

Istvan Gacsalyi

Gyula Horvath

Gabor Blasko

Judit Matuz

Lajos Toldy

Katalin Saghy

Peter Aranyi

Sandor Elek

Katalin Goldschmidt

Istvan Tarnawa

Istvan Polgari

Andras Egyed

Sandor Solyom

Andras Varro

Gyorgy Somogyi

Laszlo Sebestyen

Karoly Tihanyi

Zsuzsanna Fittler

Marta Szollosy

Andras Bilkei-Gorzo

Judit Bajnogel

Judit Sarossy Nee Kincsesy

Eva Tomori Nee Joszt

Judit Sarossy Nee Kincsessy

Krisztina Heltai

Erzsebet F Birkas

Erno Koltai

Katalin Goldschmidt Nee Horvath

Marta Rusz Nee Patfalusi

Erszebet Birkas

Franciska Erdo

Emese Csuzdl

Peter Botka, Deceased

Gabor Kapus

Erzsebet Birkas

Cecilia Salamon Haskane

Peter Korosi

Hilda Botka

Jeno Korosi, Deceased

Klara Daroczi Kazone

The invention relates to new 1-[2-(substituted vinyl)]-3,4-dihydro-5H-2,3-benzodiazepine derivatives, a process for the preparation thereof and pharmaceutical compositions comprising them. The new 1-[2-(substituted vinyl)]-3,4-dihidro-5H-2,3-benzodiazepine derivatives according to the invention correspond to the general formula (I), ##STR1## wherein the variables are hereinbelow defined: The new compounds according to the invention affect the central nervous system and can be used to advantage in the therapy.

1-[2-(substituted vinyl)]-3,4-dihydro-4-dihydro-5H-2,3-benzodiazepine

This invention relates to new 1-�2-(substituted vinyl)!-5H-2,3-benzodiazepine derivatives, a process for the preparation thereof, pharmaceutical compositions comprising the same, to the use of the said benzodiazepine derivatives for the treatment of diseases and for the preparation of pharmaceutical compositions suitable for the treatment of diseases. The compounds according to the invention correspond to the general formula (I), ##STR1## wherein the variables are herein below defined, and the compounds possess central nervous activities.

1-�2-(substituted vinyl)!-5H-2,3-benzodiazepine derivatives

3-substituted 3H-2, 3-benzodiazepine derivatives, the production and use

The invention relates to the new 1-(3-chlorophenyl)-4-hydroxymethyl-7,8-dimethoxy-5H-2,3-benzodiazepine of formula (I) ##STR1## and pharmaceutically acceptable acid addition salts thereof, furthermore to a process for preparing these compounds. The compounds according to the invention possess valuable anxiolytic, antiaggressive and antidepressant effects and have at the same time favorable acute toxicity values, so they can be used to advantage in therapy.

5H-benzodiazepin derivative

The present invention relates to novel compounds of the formula (I), ##STR1## wherein R.sub.1 and R.sub.2 stand independently from each other, for hydrogen, C.sub.1-4 alkyl, phenyl, phenyl-C.sub.1-4 alkyl, piridyl or piridyl-C.sub.1-4 alkyl group;

Novel thiouracyl derivatives, pharmaceutical compositions containing

This invention relates to new 1-(hydroxystyryl)-5H-2,3-benzodiazepine derivatives of the general formula (I) and to a process for the preparation thereof, furthermore to pharmaceutical compositions containing the same, ##STR1## wherein R stands for a hydrogen or halogen atom, or a C.sub.1-4 alkoxy group,

1-(hydroxystyrl)-5H-2,3-benzodiazepine derivatives, and pharmaceutical

This invention relates to new 3-(hydroxymethyl)-isoquinoline derivatives of the general formula (I), their acid addition salts, and to a process for the preparation thereof, furthermore to pharmaceutical compositions containing the same, ##STR1## wherein R and R.sup.1 are identical or different and stand for a hydrogen or halogen atom, a nitro or a C.sub.1-4 alkoxy group,

3-(hydroxymethyl)-isoquinoline derivatives

The invention relates to new 5H-2,3-benzodiazepine derivatives and a process for the preparation thereof, furthermore to pharmaceutical compositions containing the same. The new 5H-2,3-benzodiazepine derivatives of the invention possess valuable central nervous effect and in particular exert antiaggressive, anxiolytic, narcosis potentiating and soporific properties.

5H-2,3-benzodiazepine derivatives and pharmaceutical compositions

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Budapest, Hungary

Gabor Zolyomi