Richter Gedeon Vegyeszeti Gyar Rt

Egis Gyogyszergyar

Byogal Gyogyszergyar

Gabor Doleschall

Karoly Lempert

Gyula Hornyak

Jozsef Fetter

Karoly Zauer

Gyula Simig

Jozsef Nyitrai

Kalman Harsanyi

Gizella Barta Nee Szalai

Zsuzsanna Visky Nee Gombos

Ferenc Lorant Bartha

Lujza E Petocz

Katalin Grasser

Antal Feller

Edit Nee Berenyi

Zsuzsanna Orr

Gizella Szalai Nee Barta

Jozsef Nitrai

Gyula Siming

Peter Huszthy

Eniko Szirt

Etelka Pjeczka

Zsuzsanna Gombos Nee Visky

The invention relates to novel iminothiazolidine derivatives of the formula (I), ##STR1## wherein R.sup.1 and R.sup.3 represent, independently from each other, hydrogen or lower alkyl group,

Iminothiazolidine derivatives

The invention relates to compounds of the general formula (X) ##STR1## wherein R is as a removable protecting substituent of the amido group a phenyl group or a benzyl group substituted by one or more alkoxy group(s) having 1-4 carbon atoms and

Azetidinone acetic acid derivatives and process for the preparation

The invention relates to a process for the preparation of the compound of the formula I, ##STR1## which comprises (a.sub.1) splitting off the ethylene ketal protecting group from the azetidinone derivative of the formula IVa, ##STR2## reducing the compound of the formula III thus obtained, ##STR3## treating the resulting compound of the formula II ##STR4## with concentrated aqueous hydrogen chloride solution; or (a.sub.2) reducing the compound of the formula III, treating the compound of the formula II thus obtained with concentrated aqueous hydrogen chloride solution; or (a.sub.3) treating the compound of the formula II with concentrated aqueous hydrogen chloride solution; and isolating the compound of the formula I thus obtained from the reaction mixture. The compound of the formula I is useful as an intermediate in the production of thienamycin, a highly potent antibiotic.

Process for the preparation of aminolactone carboxylic acid

The invention relates to new heterocyclic compounds containing a protected C-acetyl group. More particularly, the invention concerns new compounds of the Formula (V) ##STR1## wherein R is a group suitable for the protection of amides;

Azetidinone-4-carboxylate containing a protected 3-acetyl group and

The invention relates to new heterocyclic compound containing an alkoxycarbonyl and a substituted methyl group a process for the preparation of these and analogeous compound and pharmaceutical compositions containing them. More particularly, the invention concerns compounds of the general formula (IVa) ##STR1## wherein R' is hydrogen, 2-ethoxycarbonylethyl, aryl or a group suitable for a temporary protection of amides and

Heterocyclic compounds containing an alkoxycarbonyl and a substituted

The invention relates to new heterocyclic compounds containing a protected C-acetyl group. More particulary, the invention concerns new compounds of the formula (VI) ##STR1## wherein R.sup.1 is hydrogen or a group suitable for a temporary protection or amides,

Beta-lactam compounds containing a protected C-acetyl group, process for

The invention relates to new heterocyclic compounds containing a C-acetyl group and a process for their preparation. More particularly, the invention concerns new compounds of the formula (III). ##STR1## in which R is a protecting group suitable for temporary protection of amines and amides or an aryl group, and Z is alkyl. The compounds are intermediates in the preparation of penicillins.

Beta-lactam compounds containing a C-acetal group and process for their

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Budapest, Hungary

Gabor Doleschall