Egis Gyogyszergyar Rt.

Richter Gedeon Vegyeszeti Gyar Rt

International Business Machines Corporation

Egis Gyogyszergyar

Egis Pharmaceutical

Gis Gyogyszergyar Rt.

Egis Gyoyszergyar Rt

Gabor Blasko

Gyula Simig

Andras Egyed

Zoltan Budai

Istvan Gacsalyi

Katalin Szemeredi

Tibor Mezei

Istvan Gyertyan

Marton Fekete

Gabor Gigler

Klara Reiter Nee Esses

Csaba Szantay

Daniel Bozsing

Eva Schmidt

Karoly Tihanyi

Andras Bilkei-Gorzo

Judit Bajnogel

Bela Stefko

Janos Kreidl

Eniko Szirt Nee Kiszelly

Erik Bogsch

Jozsef Reiter

Kalman Nagy

Imre Klebovich

Andras Nemes

Ivan Beck

Istvan Hegedus

Margit Csorgo

Andras Vedres

Agnes Kovacs Nee Palotai

Andras Dietz

Geza Schneider

Denes Mathe

Gabriella Rmos Nee Lassu

Tamas Mester

Ilma Dinnyes Nee Nagy

Klara Kazo Nee Daroczi

Lujza E Petocz

Gabor Kovacs

Imre Moravcsik

Attila Mandi

Ferenc Andrasi

Jozsef Barkoczy

Tamas Hamori

Gabor Nemeth

Pal Berzsenyi

Gabor Zolyomi

Peter Tompe

Maria Szecsey Nee Hegedus

Lajos Novak

Pal Vago

Gyula Lukacs

Katalin Pallagi

Gyorgy Krasznai

Judit Kun

Eva Furdyga

Eszter Szentkuti

Laszlo Gaal

Endre Rivo

Gabor Makara

Elemer Jakfalvi

Sandor Drabant

Katalin Horvath

Anna Bakonyi

Norbert Nemeth

Peter Kovacs

Geza Szabo

Imre Doman

Szilveszter E Vizi

Enik Szirt Nee Kiszelly

Chandrasekhar Naravanaswami

Ilona Sztruhar

Klara Gado

Aniko Miklos Nee Kovacs

Zoltan Ratkai

Edit Horvath

Gyorgyne Mate

Gyorgyi Donath Vereczkey

Adrien Szuchovszky, Nee Gergely

Elemer Jakflavi

Laszlo Koncz

Gyongyi Vereczkey Nee Donath

Judit Szego

Ivan Jakoczi

Luiza Petocz

Ildiko Ratz Nee Simonek

Klara Reiter Nee Eszes

Ludmilla Rohacas Nee Zamkovaja

Erika Karaffa

Aniko Kovacs

Eniko Szirt Nee Kislelly

Erzsebet Kaufmanne Bojti

Kalara Reiter Nee Esses

Andras Bilkei Gorzo

Miklos Abermann

Katalin Baloghne Nemes

Bernadett Martonné Marko

Gyula Grezal

György Levay

Annamaria Simo

An interface for a small form factor electronic device by enabling explicit measurement of extension or retraction of a retractable cord by monitoring the amount of string that passes by sensors, as the string exits the enclosure of the device. Input to such small form factor devices may be provided by sensors that measure the length of a string or wire that has been pulled out of an enclosure, in addition to an angle or direction (e.g., in 1-, 2- or 3-dimensions) at which the string was pulled out. Additionally, the rate of acceleration for the pulling and retracting motion may also be used as additional forms of input. In a further embodiment, a string interface is provided for a small form factor device that communicates information in the form of a pixel display provided integral with the string in response to string manipulation.

Retractable string interface for stationary and portable devices

The invention relates to new 2,3-benzodiazepine derivatives of general Formula (I), (wherein Rstands for methyl, formyl, carboxy, cyano, &#x2014;CH&#x2550;NOH, &#x2014;CH&#x2550;NNHCONHor &#x2014;NRR, wherein Rand Rindependently from each other represent hydrogen or lower alkyl or together with the nitrogen atom, they are attached to, form a 5- or 6-membered, saturated or unsaturated heterocyclic ring optionally containing one or more further nitrogen, sulfur and/or oxygen atom(s); Ris nitro or amino; Rstands for hydrogen, lower alkanoyl or CO&#x2014;NRR, wherein Rand Rindependently from each other stand for hydrogen, lower alkoxy, lower alkyl or lower cycloalkyl or together with the nitrogen atom, they are attached to, form a 5- or 6-membered, saturated or unsaturated heterocyclic ring optionally containing one or more further nitrogen, sulfur and/or oxygen atom(s); Ris hydrogen or lower alkyl; the dotted lines have the following meaning: if Rand Rare not present, the bond between positions Cand Cis a single bond and the bond between positions Cand Nis a double bond; if Rand Rare present, the bonds between positions Cand Cand between position Cand Nare single bonds; and if Ris present and Ris missing, the bond between positions Cand Cis a double bond and the bond between positions Cand Nis a single bond) and salts thereof. The invention compounds have neuroprotective effect.

2,3-benzodiazepine derivatives

Piperazinylalkylthiopyrimidine derivatives, pharmaceutical compositions

1,7,7-trimethyl-bicyclo[2.2.1]heptane derivatives as anxiolytic agents

The invention relates to a new process for the preparation of amlodipine besylate of the Formula ##STR1## Amlodipine besylate of the Formula I is a valuable known blood pressure decreasing antianginal agent. The advantage of the process of the present invention is that it can be carried out in a simple way with high yields and there is no need to isolate the amlodipine base.

Process for the preparation of a dihydropyridine derivative

This invention relates to new 1-�2-(substituted vinyl)!-5H-2,3-benzodiazepine derivatives, a process for the preparation thereof, pharmaceutical compositions comprising the same, to the use of the said benzodiazepine derivatives for the treatment of diseases and for the preparation of pharmaceutical compositions suitable for the treatment of diseases. The compounds according to the invention correspond to the general formula (I), ##STR1## wherein the variables are herein below defined, and the compounds possess central nervous activities.

1-�2-(substituted vinyl)!-5H-2,3-benzodiazepine derivatives

Acid amide derivatives and process for the preparation thereof

The invention relates to anxiolytic pharmaceutical compositions comprising as active ingredient 1-sytrylisoquinoline derivatives of general formula (I), wherein

Heterocyclic compounds, pharmaceutical compositions comprising them and

This invention relates to new oxaindene derivatives, a process for the preparation thereof and pharmaceutical compositions comprising the same. The compounds according to the invention are characterized by the general formula (1) ##STR1## wherein R.sup.1 represents lower C.sub.1-4 alkyl, lower C.sub.1-4 alkoxy or lower C.sub.3-6 cycloalkyl,

Oxaindene derivatives and process for the preparation thereof

The invention refers to a pharmaceutical composition, a process for the preparation thereof and a novel medical use of bicycloheptane derivatives. The pharmaceutical compositions of the invention comprise a bicycloheptane derivative of the formula I ##STR1## wherein said derivative is as defined in the specification herein. The pharmaceutical compositions of the invention are suitable for the treatment of diseases and disorders that are connected with the influence on the cholecystokinin system, especially for preventing the spastic contraction of the gallbladder.

Pharmaceutical compositions containing bicycloheptane ether amines and a

The invention refers to pharmaceutical compositions for the prevention and/or treatment of gastrointestinal diseases connected with infections caused by Helicobacter pylori and a method for the treatment of such diseases. The pharmaceutical composition of the invention comprises as active ingredient a cyclic ketone derivative of the formula I ##STR1## wherein and R.sup.1 mean independently hydrogen or halo;

Pharmaceutical compositions for the prevention and/or treatment a

The invention relates to novel, pharmaceutically active trisubstituted cycloalkane derivatives, a process for the preparation thereof and pharmaceutical compositions comprising the same. The invention also encompasses the use of the said cycloalkane derivatives for the treatment of diseases and for the preparation of pharmaceutical compositions suitable for the treatment of diseases. The compounds according to the invention are characterized by the general formula (I), ##STR1## wherein R represents hydrogen, C.sub.1-4 alkyl or hydroxyl,

Trisubstituted cycloalkane derivatives and process for the preparation

Novel basic ether of general formula (I), ##STR1## wherein R.sup.1 and R.sup.2 are independently hydrogen, halogen or C.sub.1-4 alkoxy, or together they represent a 3,4-methylenedioxy group,

Basic ethers and process for the preparation thereof

Process for the preparation of 8 -[4 -[4-(pyrimidine-2-yl)-piperazine-1-yl]-butyl]-8-aza-spiro[4.5]decane-7,9-d ione (buspiron) of the Formula I ##STR1## and the hydrochlorides thereof having high purity by continuously adding a solution of 8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl]-but-2 -inyl]-8-aza-spiro[4.5]decane-7,9-dione of the formula II ##STR2## formed with an inert organic solvent having a concentration of at least 40% by weight to a suspension of a hydrogenation catalyst in an inert organic solvent and optionally converting the 8-[4-[4-(pyrimidine-2-yl)-piperazine-1-yl]-butyl]-8-aza-spiro[4.5]decane-7 ,9-dione thus obtained into the hydrochloride thereof.

Process for the preparation of high purity buspiron and the

The invention relates to novel, pharmaceutically active benz[e]indene derivatives, a process for the preparation thereof, pharmaceutical compositions comprising the same, further to the use of the said benz[e]indene derivatives in the treatment of certain diseases and in the preparation of pharmaceutical compositions suitable for the treatment of said diseases. The new benz[e]indene derivatives according to the invention correspond to the general formula ##STR1## wherein A represents a group of the formula alk-NR.sup.1 R.sup.2, wherein alk represents a C.sub.2-7 alkylene group optionally carrying a hydroxy substituent,

Benz[e]indene derivatives

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Budapest, Hungary

Gabor Blasko