King Faisal Specialist Hospital & Research Centre

Futwan Al-Mohanna

Eid Abdullah Al Mutairy

Mohammed Khalid

Katharine Collison

Soad Saleh

Uday Kishore

Praveen Mathews Varghese

Valarmathy Murugiah

Ranjit Parhar

Reem Al-hejailan

Razan Bekheet

Kate Collison

Girish J Kotwal

The invention is directed to a method for diagnosing and treating a pulmonary lung disease by detecting a mutant S100A3 protein associated with pulmonary lung disease and by treating a subject with a functional S100A3 protein.

Method for treating pulmonary fibrosis using S100A3 protein

The invention is directed to a method for diagnosing and treating fibrosis, especially pulmonary fibrosis, associated with mutation of the S100A13 and S100A3 genes. Methods for detecting and distinguishing the mutant forms of these genes are disclosed and ways to compensate for loss of function or aberrant function of the mutated S100A13 or S100A3 proteins are disclosed.

Method for diagnosing or treating pulmonary fibrosis using S100A13 protein

The present invention further relates to using vaccinia virus complement control protein (VCP), factor H and/or a complement control protein (CCP)-containing protein as modulator of the entry and/or replication of pathogen(s), wherein the pathogen is a virus or bacteria. The present invention further relates to a method of prevention and/or treatment of influenza A virus (IAV) infection in a subject of need thereof and to a method of modulation of the entry and/or replication of pathogen(s) in a subject of need thereof.

VCP and factor H as viral entry inhibitors

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Riyadh, Saudi Arabia

Futwan Al-Mohanna