Phc Holdings Corporation

Fusatoshi Okamoto

Masahiro Johno

Kazuya Kondoh

Masanori Tanaka

Masayuki Saiki

Kouji Nino

This substrate for sample analysis, which transfers a sample-containing liquid by means of rotation and analyzes a specific substance in a sample, is provided with: a space which holds the sample-containing liquid in a substrate having a rotary shaft; a reaction chamber having an inlet and an outlet connected to the space; and a dried reagent disposed in the space of the reaction chamber. The space has a first end and a second end spaced apart from each other in a circumferential direction. The inlet and the outlet are arranged at the first end and the second end, respectively. The space has a capillary portion, and a first non-capillary portion which is connected to the capillary portion, is located at the second end, has an opening, and extends in a radial direction. The outlet is connected to the outer peripheral side of the first non-capillary portion.

Substrate for sample analysis

A sample analysis substrate capable of holding a plurality of liquids. The sample analysis substrate has a microchannel structure for transferring a liquid through rotary motion, the sample analysis substrate including: a substrate body having a rotation axis; a first and a second container holding a first and a second liquid therein; a first and a second accommodating section accommodating the first and the second container; and a cap having a first and second projection and movably supported on the substrate body. As the cap moves, the first drive projection and the second drive projection move the first container and the second container with staggered timing, thereby releasing the first and the second liquid accommodated therein.

Sample analysis substrate

A sample analysis substrate includes a substrate; a first holding chamber; a reaction chamber; a first flow path having a first opening and a second opening respectively connected with the first holding chamber and reaction chamber; a main chamber; a second flow path having a third opening and a fourth opening respectively connected with the reaction chamber and the main chamber; and a magnet accommodation chamber capable of accommodating a magnet. The first opening is located closer to a rotation shaft than the second opening. The second opening is located closer to the rotation shaft than the third opening. The magnet accommodation chamber is located at a position at which, in the case where the magnet is accommodated in the magnet accommodation chamber, the magnet captures magnetic particles in the main chamber. The sample analysis substrate is rotatable to transfer a liquid.

Specimen analysis substrate, specimen analysis device, specimen analysis system, and program for specimen analysis system

A sample analysis substrate rotatable to transfer a liquid includes a substrate including a rotation shaft, a first holding chamber, a second holding chamber holding a first liquid discharged from the first holding chamber, a main chamber holding the first liquid discharged from the second holding chamber, a first flow path with the first holding chamber and the second holding chamber, and a second flow path having a third opening and a fourth opening respectively connected with the second holding chamber and the main chamber. The first holding chamber includes a portion farther from the rotation shaft than a position thereof connected with the first opening. The second holding chamber includes a portion farther from the rotation shaft than a position thereof connected with the second opening. In the second flow path, the third opening is closer to the rotation shaft than the fourth opening.

Sample analysis substrate, sample analysis device, sample analysis system, and program for sample analysis

A substrate for sample analysis is a substrate for sample analysis used for causing a binding reaction between an analyte and a ligand in a liquid sample, the substrate for sample analysis including: a base substrate having a rotation axis and a predetermined thickness; a chamber located in the base substrate for holding a liquid sample containing an analyte and a ligand immobilized on a surface of magnetic particles; and at least one magnet arranged at a position such that the magnetic particles are captured in the chamber by the magnet.

Substrate for sample analysis, and sample analysis apparatus

A substrate for sample analysis on which transfer of a liquid is to occur with rotational motion includes: a substrate having a rotation axis; a first chamber being located in the substrate and having a first space for retaining a liquid and magnetic particles; a second chamber being located in the substrate and having a second space for retaining the liquid to be discharged from the first chamber; a channel being located in the substrate and having a path connecting the first chamber and the second chamber; and a magnet being located in the substrate and near the first space in the substrate for capturing the magnetic particles in the first chamber.

Substrate for sample analysis, sample analysis device, sample analysis system, and method for removing liquid from liquid that contains magnetic particles

A substrate for sample analysis including: a substrate including a rotation axis; a first chamber, which includes a first space which retains the liquid; a second chamber, which includes a second space which retains the liquid discharged from the first chamber; and a first flow passage, which includes a path connecting the first chamber and the second chamber in which the first flow passage has a first opening and a second opening, the first opening and the second opening are connected to the first chamber and the second chamber, respectively, and the first opening is positioned on a side closer to the rotation axis than the second opening, in which the first space includes a first region, which includes a portion extending from the first opening and in which the first space of the first chamber has a capacity larger than a capacity of the first flow passage.

Substrate for sample analysis, sample analysis device, sample analysis system, and program for sample analysis system

A substrate for sample analysis on which transfer of liquids is to occur with rotational motion, includes a substrate having a rotation axis; a first chamber and a second chamber being located in the substrate and respectively having a first space and a second space for retaining a first liquid and a second liquid; a third chamber being located in the substrate and having a third space for retaining the liquids to be discharged from the first chamber and the second chamber; a first channel having a path connecting the first chamber and the third chamber to transfer the first liquid; and a second channel having a path connecting the second chamber and the third chamber to transfer the second liquid.

A substrate for sample analysis has a rotation axis, a first chamber having a first space for retaining a liquid, a second chamber having a second space for retaining the liquid to be discharged from the first chamber, and a first channel having a path connecting the first chamber and the second chamber. The first space includes a first portion and a second portion, and a coupling portion located between the first and second portions. The substrate includes a wall portion partitioning the first and second portions from each other. The second chamber is more distant from the rotation axis than is the first portion. The coupling portion is closer to the rotation axis than is the wall portion. The second portion at least includes a portion which is more distant from the rotation axis than is the first portion.

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Ehime, Japan

Fusatoshi Okamoto