Kyorin Pharmaceutical Co., Ltd.

Teijin Pharma Limited

Fumiyoshi Kobayashi

Shinji Kobayashi

Masanori Yamamoto

Yasumichi Fukuda

Yoshikazu Asahina

Tomohiro Ide

Kanji Komatsu

Kenji Fujita

Kohei Ohata

Naoki Ando

Hiroyuki Miyachi

Masanori Takadoi

Ayako Nakamura

Masato Hoshino

A compound represented by the following formula (1): (wherein the carbon atom denoted by * is in the R-configuration; Rand Rare each independently a hydrogen atom, a halogen atom, an amino group, a hydroxyl group, a hydroxyamino group, a nitro group, a cyano group, a sulfamoyl group, a C-Calkyl group, a C-Calkoxy group, a C-Calkylsulfanyl group, a C-Calkylsulfinyl group or a C-Calkylsulfonyl group; and A is a substituted or unsubstituted heteroaryl group), or a pharmaceutically acceptable salt thereof.

Glucokinase activator

A compound, or a pharmaceutically acceptable salt thereof, represented by the formula (1), (wherein, the carbon atom marked with an * is in the R-configuration, Rrepresents a hydrogen atom, a halogen atom, an amino group, a hydroxyl group, a hydroxyamino group, a nitro group, a cyano group, a sulfamoyl group, a C-Calkyl group, or a C-Calkoxy group, Rrepresents a C-Ccycloalkylsulfanyl group, a C-Ccycloalkylsulfinyl group, or a C-Ccycloalkylsulfonyl group, and A represents a substituted or unsubstituted heteroaryl group).

N-substituted pyrrolidine derivatives and process for preparing the same

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Tochigi, Japan

Fumiyoshi Kobayashi