Kaneka Corporation

Kanegafuchi Kagaku Kogyo Kabushiki Kaisha

Other

Fumiyasu Hirai

Nobutaka Tani

Shigeo Furuyoshi

Takashi Asahi

Tamiji Fujimoto

Eiji Ogino

Hiroshi Sakurai

Takamune Yasuda

Kohei Fukaya

Michio Nomura

Hidekazu Miyauchi

Mariko Matsumoto

Takehiro Nishimoto

Chihiro Koga

Osamu Odawara

Hiroyuki Maruyama

Takayuki Sakogawa

Yuji Okubo

A lacrimal duct tube includes: a pair of tubular members that each have at one end an opening communicating with a lumen; and a connection member that connects the other ends of the tubular members. A base end part including the other end of at least one of the tubular members is tapered down toward the connection member and the base end part has an inlet/outlet port communicating with the lumen of the tubular member. A portion of the base end part constituting peripheral edge of the inlet/outlet port and the connection member are connected together.

Lacrimal duct tube

The invention aims at providing an adsorbent for bacterial toxins, a method for removal of such toxins by adsorption, and an adsorber packed with said adsorbent. Provided are an adsorbent for bacterial toxins,

Bacterial toxin adsorbing material, method of removing the toxin by adsorbing, and an adsorber formed by filling the adsorbing material therein

An adsorbent which comprises a water-insoluble carrier and a compound, which is immobilized on said carrier, having a binding affinity for an antibody against &#x3b2;1-adrenoceptor and/or an antibody against M2 muscarinic receptor exhibits a remarkably large adsorptive capacity.

Adsorbents for dilated cardiomyopathy

The present invention is directed to an enterotoxin adsorbent comprising a compound having a log P (P denotes a partition coefficient in an octanol-water system) value of not less than 2.50 as immobilized on a water-insoluble carrier.

Enterotoxin adsorbent, method of adsorptive removal, and adsorption apparatus

An adsorbent for peptidoglycan which comprises an water-insoluble porous material having an amino group and having a molecular weight of exclusion limit of at least 50,000, and a method for removing peptidoglycan by adsorption, which comprises a step of contacting the adsorbent to a liquid containing peptidoglycan.

Adsorbent for peptidoglycan and method and apparatus for adsorptively removing peptidoglycan

An adsorbent suitable for adsorption of a transforming growth factor-&#x3b2; (TGF-&#x3b2;) comprising a compound which has a log P value of at least 2.50 wherein P is a partition coefficient in an octanol-water system and which is immobilized on a water-insoluble carrier. TGF-&#x3b2; present in a body fluid can be efficiently removed by bringing the body fluid into contact with the adsorbent.

Method for removing the transforming growth factor-&#x3b2; by adsorption

There are provided an adsorbent which can effectively adsorb and remove endogenous cannabinoid in fluid, and a process for removing endogenous cannabinoid in fluid by means of the adsorbent. The adsorbent of endogenous cannabinoid comprising an adsorbent for endogenous cannabinoid comprising a water-insoluble material containing a substance whose solubility parameter &dgr; is at most 12 ((cal/cm ) ) is obtained. Endogenous cannabinoid in fluid can be effectively adsorbed and removed by contacting the adsorbent of endogenous cannabinoid with fluid containing endogenous cannabinoid.

Process for adsorbing and removing endogenous cannabinoid

There are provided an adsorbent which can effectively adsorb and remove endogenous cannabinoid in fluid, and a process for removing endogenous cannabinoid in fluid by means of the adsorbent. The adsorbent of endogenous cannabinoid is obtained by fixing a compound having a log P value (P indicating distribution coefficient in octanol-water system) of at least 3.50 on a water-insoluble carrier. Endogenous cannabinoid in fluid can be adsorbed and removed in an effective manner by contacting the adsorbent of endogenous cannabinoid with fluid containing endogenous cannabinoid.

Adsorbent, adsorbing and removing process and adsorber for endogenous cannabinoid

An adsorbent or bradykinin comprising styrene-divinylbenzene copolymer having sulfonic acid groups and a method for adsorbing and removing bradykinin comprising contacting the adsorbent with a fluid containing bradykinin are provided. An adsorber for adsorbing bradykinin in which the adsorbent is charged in a vessel having an inlet and an outlet for a fluid is also provided.

Adsorbent for bradykinin, method for eliminating the same by adsorption, and adsorber

An adsorbent for toxic shock syndrome toxin-1 (TSST-1) comprising a compound which has a log P value of at least 2.50 wherein P is a partition coefficient in an octanol-water system and which is immobilized on a water-insoluble carrier; a method for removing TSST-1 body fluids by adsorption which comprises bringing a body fluid containing TSST-1 into contact with the adsorbent; an adsorber for TSST-1 comprising an adsorbent packed in a container having an inlet and an outlet for a body fluid and a means for preventing the adsorbent from flowing out of the container; and use of the adsorbent. TSST-1 in body fluids can be efficiently removed by the adsorbent.

Method for removing toxic shock syndrome toxin-1 in body fluids by adsorption

An endotoxin adsorption system of the present invention comprises a combination of a cation exchange resin having sodium as a counter ion and a cation exchange resin having sodium and one or more metal ions other than sodium as a counter ion, and adsorbs an endotoxin without decreasing of the concentration of cations.

Endotoxin adsorption system

The present invention relates to an adsorbent being capable of efficiently removing tumor necrosis factor-.alpha. (TNF-.alpha.) in a body fluid, an adsorber using the adsorbent and a process for adsorbing and removing TNF-.alpha., namely an adsorbent of TNF-.alpha., wherein onto a water-insoluble carrier a compound having a functional group represented by the formula (I): ##STR1## wherein X.sup.- is an anionic functional group, A is a substituent group except for the anionic functional group, n is an integer of 0 to 4 and in case n is at least 2, groups A, the number of which is n, may be the same or different from each other; a process for adsorbing and removing TNF-.alpha., which comprises coming the adsorbent into contact with a body fluid; and an adsorber for adsorbing TNF-.alpha. wherein a vessel having an inlet and an outlet for a body fluid and being equipped with a means for preventing the adsorbent from flowing to the outside of the vessel, is charged with the adsorbent.

Process for adsorbing and removing tumor necrosis factor-.alpha.

An adsorbent for a serum amyloid protein, which comprises a water-insoluble carrier and either a compound selected from the group consisting of a compound having an anionic functional group, a polyanionic compound having more than one anionic functional groups, aniline and an aniline derivative, said compound being immobilized onto said carrier, or a group of the formula: --NR.sup.1 R.sup.2, wherein R.sup.1 is hydrogen atom, methyl group or ethyl group, and R.sup.2 is an atomic group satisfying that the value of log P, in which P is a distribution coefficient in a water-octanol system, of a compound of the formula: R.sup.2 H is from 0 to 3.2, said group being bonded to said carrier, and a method for removing a serum amyloid protein from body fluid through a removing apparatus using the above adsorbent. According to the present invention, SA proteins, particularly SAA proteins and SAP proteins can be selectively removed from body fluid without decreasing HDL largely. Besides, the adsorbent can be provided at a low cost.

Adsorbent for serum amyloid protein

Adsorbent of interleukins, process for removing the same, and adsorber

An adsorbent for a serum amyloid protein, which includes a water-insoluble carrier and either a compound selected from a compound having an anionic functional group, a polyanionic compound having more than one anionic functional groups, aniline and an aniline derivative, the compound being immobilized onto the carrier, or a group of the formula: --NR.sup.1 R.sup.2, wherein R.sup.1 is hydrogen atom, methyl group or ethyl group, and R.sup.2 is an atomic group satisfying that the value of log P, in which P is a distribution coefficient in a water-octanol system, of a compound of the formula: R.sup.2 H is from 0 to 3.2, the group being bonded to the carrier, and a method for removing a serum amyloid protein from body fluid through a removing apparatus using the above adsorbent. According to the present invention, SA proteins, particularly SAA proteins and SAP proteins can be selectively removed from body fluid without decreasing HDL largely. Besides, the adsorbent can be provided at a low cost.

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Ibaraki, Japan

Fumiyasu Hirai