Olympus Optical Company, Ltd.

Fumio Uchino

Hitoshi Tateoka

Yuzo Nakamura

Masahiro Ohno

Kouichi Karaki

Soji Yamamoto

Tatsuo Nagasaki

Akihiro Namba

Mitsugu Sakai

Outaro Ando

Takeshi Yamagishi

Hiroshi Kajimura

Koichi Karaki

Kiyoshi Fujii

Junichi Ishibashi

Kanae Nakasato

Yasushi Satoh

Jun-ichi Ishibashi

Masako Hacchow

Kouji Taguchi

In an acoustic lens apparatus of this invention, a lens surface formed on an ultarsonic medium has a longitudinal wave lens portion constituted by a first aspherical surface at its central area, and a transverse wave lens portion constituted by a second aspherical surface at its peripheral area. The ultrasonic medium includes a piezoelectric transducer for generating ultrasonic waves at its surface opposite to the lens surface. The ultrasonic medium is arranged so that the lens surface opposes a sample, a coupler medium is filled in the gap between the surface and the sample.

Acoustic lens apparatus

An acoustic lens for use in an acoustic microscope including a solid state medium for propagating an acoustic wave having a wavelength .lambda. and having opposed end surfaces, an electric-acoustic transducer applied on one end surface of the solid state medium and having a radius a, and a spherical lens portion formed in the other end surface of the solid state medium and having an aperture of a radius w. The length l and the aperture radius w are normalized by the transducer radius a such that Z=l.lambda./a.sup.2 and W=w/a. Values of Z and W are selected from such a region in a first quadrant of the Z-W coordinate system that desired power and/or phase are obtained. The region neighboring the point Z=1 and W=1 is excluded.

Acoustic lens for use in acoustic microscope

Ultrasonic microscope

A coherent laser light flux is projected into a cell made of transparent quartz and light scattered from particles suspended in an antigen-antibody reaction liquid contained in the cell is detected by a photomultiplier by means of a collimator. An output electrical signal from the photomultiplier is sampled at different time instances and samplings are supplied to a fast Fourier transformer to derive a plurality of power spectrum desnities of fluctuation in intensity of the scattered light. A plurality of power spectrum densities are averaged to generate a mean power spectrum density. An amount of antigen contained in the reaction liquid is measured in accordance with the mean power spectrum density.

Method and apparatus for measuring immunological reaction with the aid

A coherent laser light flux is projected into a cell made of transparent quartz and light scattered from particles suspended in an antigen-antibody reaction liquid contained in the cell is detected by a photomultiplier by means of a collimator. An output electrical signal from the photomultiplier is sampled at different time instances and samplings are supplied to a fast Fourier transformer to derive a plurality of power spectrum densities of fluctuation in intensity of the scattered light. A plurality of power spectrum densities are averaged to generate a mean power spectrum density. An amount of antigen contained in the reaction liquid is measured in accordance with the mean power spectrum density.

In order to replace acoustic lenses, frequency units corresponding to frequencies used by the acoustic lenses and housing transmitted pulse generating means, circulators and receiving means can be selected and the signal of a gate opening at a timing at which ultrasonic waves of a sample return can be selected.

A microscope having an optical head and an additional head is disclosed. A slide plate on which the additional head and optical head are arranged in such a manner that they are separated by a predetermined spacing in the Y direction is slidably secured to an arm of the microscope. Under such a construction, an observation by a raster image and an optical observation by a optical image can be performed precisely for the same region of a specimen by moving the additional head and optical head integrally by a distance substantially equal to the spacing by means of the slide plate.

Microscope having an optical head and an additional head

An apparatus for displaying ultrasonic images picked-up by an ultrasonic microscope including a digital scan converter having three image memories for storing successively picked-up three ultrasonic images. The digital scan converter functions to reconstruct a color image from the three ultrasonic images by simultaneously reading ultrasonic image signals out of the image memories as red, green and blue color signals.

Apparatus for displaying ultrasonic image

An ultrasonic microscope having an ultrasonic head and an optical head is disclosed. A slide plate on which the ultrasonic head and optical head are arranged in such a manner that they are separated by a predetermined spacing in Y direction is slidably secured to an arm of the ultrasonic microscope. Under such a construction, an ultrasonic observation by an ultrasonic raster image and an optical observation by an optical image can be performed precisely for the same region of a specimen by moving the ultrasonic head and optical head integrally by a distance substantially equal to the spacing by means of the slide plate.

A mechanism for attaching an ultrasonic head of an ultrasonic microscope to a vibration shaft of a vibrator is disclosed. A first connector half to which an R.F. cable is connected is fixedly arranged to the vibration shaft and a second connector half having the ultrasonic head coupled therewith is detachably attached to the first connector half, so that an exchange of the ultrasonic head can be performed in an easy and swift manner without affecting the position and characteristics of the R.F. cable.

Growing community of inventors

Hachioji, Japan

Fumio Uchino