Nof Corporation

Kyoto Institute of Technology

National University Corporation Kyoto Institute of Technology

Fumio Nakashima

Satoshi Yamada

Tomozumi Noda

Nobuyuki Sakamoto

Masaru Matsuda

Yoichi Kumada

Yasutaka Kawaguchi

Aranna Nemoto

A protein adsorption inhibitor includes a compound of Formula (1) as an active ingredient. The protein adsorption inhibitor is capable of highly inhibiting non-specific adsorption of a protein such as an antibody or an enzyme to a surface of a base body such as an immune reaction vessel or an assay instrument. Also provided is a coating layer-formed base body having a coating layer containing the protein adsorption inhibitor on the base body. The coating layer-formed base body has an excellent protein adsorption-inhibiting function. A method for inhibiting the adsorption of the protein to the base body is provided. The method includes forming the coating layer containing the protein adsorption inhibitor on the surface of the base body: wherein, X is a hydrogen atom or a methyl group and n is an integer of 9 to 15.

Protein adsorption inhibitor and method for inhibiting protein adsorption

Provided is a novel method of suppressing non-specific protein adsorption. The above-mentioned object can be achieved by treating a solid phase with a solid phase-treating liquid containing a phosphorylcholine group-containing polymer as a main component, and treating a specimen with a specimen-treating liquid containing, as a main component, a polymer having a phosphorylcholine group, a hydroxy group, and a hydrophobic group, followed by addition of the treated specimen to the treated solid phase.

Method for suppressing protein adsorption

An object is to provide a method of manufacturing a vessel for embryoid body formation excellent in formability of an embryoid body and suitable for optical observation.

Method for producing container for forming embryoid body

There is provided a protein stabilizer containing a compound represented by Formula (1) as an active ingredient. The protein stabilizer is capable of stabilizing a protein in a solution state for a long period of time without affecting an assay system, the protein being not limited to enzymes, labeling substances such as fluorescent substances and chemiluminescent substances, and assay target substances. There is also provided a protein stabilization method containing making the protein coexist with the compound represented by Formula (1) in a water-containing solution.  In Formula (1), X is a hydrogen atom or a methyl group, and n is an integer of 3 to 17.

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Kawasaki, Japan

Fumio Nakashima