Taiho Pharmaceutical Company Limited

Fumihito Hosoi

Takeshi Sagara

Satoru Iguchi

Daisuke Kajiwara

Yoshinori Nakachi

Provided is a preventive and/or therapeutic agent for immune diseases containing a compound having a BTK inhibitory activity or a salt thereof, as an active ingredient. A preventive and/or therapeutic agent of immune diseases, comprising a compound represented by Formula (I), where Rto R, W, X, Y, Z, and n represent those as defined in the specification, or a salt thereof, as an active ingredient. 

Preventive and/or therapeutic agent of immune disease

Provided is a novel compound having BTK inhibitory action and a cell proliferation suppressing effect. Also provided is a medicine useful for the prevention and/or treatment of a disease associated with BTK, particularly cancer, based on BTK inhibitory action. A compound represented by formula (I) [wherein Rto R, W, A, Y and Z respectively have the meanings as defined in the specification], or a salt thereof is disclosed. 

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Tsukuba, Japan

Fumihito Hosoi