Nikon Corporation

The University of Tokyo

Tokyo Institute of Technology

Fumi Kano

Masayuki Murata

Yoshiyuki Noguchi

Masafumi Yamashita

Shoko Yamasaki

Takuro Saigo

Mamiko Masutani

Nobuhiko Maiya

Chisako Iwamoto

Kenta Imai

Shinichi Furuta

Hirotada Watanabe

Wataru Tomosugi

Kenichi Ohba

Shunsuke Takei

Yuki Sonoda

An image processing device includes a determination unit configured to determine a type of autophagy induced in a cell, based on information indicative of autophagic activity in the cell present in a cell image in which the cell is image captured and based on information indicative of congestion of molecules in the cell present in the cell image.

Image processing device, analysis device, image processing method, image processing program, and display device

The object of the present invention is to provide a method for incorporating an arbitrary protein, lipid, carbohydrate, or nucleic acid into an exosome. The object can be solved by a method for preparing an exosome, comprising the steps of: (a) adding a biological toxin having a perforating activity to a medium containing cells and incubating the mixture, (b) adding ATP and incubating the mixture, and (c) adding a medium containing calcium ion and incubating the mixture.

Method for producing exosomes and exosomes obtained thereby

An analysis device configured to analyze a correlation between feature values in a cell in response to a stimulus includes: a cell-image acquiring unit configured to acquire a plurality of cell images in which the cell that is stimulated is captured; a feature value calculating unit configured to calculate a feature value for constituent elements that form the cell, based on the plurality of cell images acquired by the cell-image acquiring unit; a correlation calculating unit configured to use the feature value calculated by the feature value calculating unit and to calculate correlations between the constituent elements; a correlation selecting unit configured to select a first correlation from the correlations calculated by the correlation calculating unit; and an image selecting unit configured to select a first cell image from the plurality of cell images that are captured, based on the first correlation that is selected.

Analysis device, analysis method, analysis program and display device

An analysis device configured to analyze an attribute of a correlation between responses with respect to a stimulus to a first subcellular component that is a subcellular component of a cell and a second subcellular component different from the first subcellular component, the analysis device including an attribute analysis unit that analyzes the attribute of the correlation between the first subcellular component and the second subcellular component based on a first change in a feature value of the second subcellular component with respect to the stimulus in a state a function of the first subcellular component is suppressed and a second change in a feature value of the second subcellular component with respect to the stimulus in a state the function of the first subcellular component is not suppressed.

Analysis device, analysis program, and analysis method

An image-processing device including: a determination unit that determines a captured image on the basis of a ratio of cells and a distribution of the cells in the captured image acquired by imaging a sample including cells; and an area setting unit that sets an area used for analyzing the cells of the sample on the basis of a result of the determination acquired by the determination unit.

Image-processing device, image-processing method, and image-processing program for setting cell analysis area based on captured image

An analysis device includes: a cell image acquisition unit that acquires a plurality of cell images in which a stimulated cell has been captured; a feature value calculation unit that calculates a feature value for each of first and second constituent elements constituting the cell, from the cell images acquired by the cell image acquisition unit; a correlation calculation unit that calculates correlations between first feature values and between second feature values in the first and second constituent elements calculated by the feature value calculation unit; a correlation extraction unit that extracts the correlation between the first feature values by selecting the first feature values with respect to the correlations between the feature values in the first and second constituent elements calculated by the correlation calculation unit; and a display unit that displays the correlation between the first feature values extracted by the correlation extraction unit.

Analysis device, analysis method, and program

An analysis device includes an acquisition unit configured to acquire an image of a cell and an identification unit configured to identify elements that are identifiable on the basis of the image of cell acquired by the acquisition unit. Characteristic quantities of the elements identified by the identification unit are calculated, a correlation between the characteristic quantities is calculated on the basis of the calculated characteristic quantities of the elements, and a correlation between the elements is calculated on the basis of the calculated correlation between the characteristic quantities.

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Tokyo, Japan

Fumi Kano