Micreos Human Health B.v.

Fritz Eichenseher

Martin Johannes Loessner

Mark Leonard Offerhaus

The present invention relates to the field of medicine, specifically the field of bacterial infection and treatment thereof.

Combination of bactericidal agent with a lysosomotropic alkalinising agent for the treatment of a bacterial infection

The invention relates to the field of medicine, specifically to the field of treatment of conditions associated withinfection. The invention relates to a novel endolysin polypeptide specifically targeting a bacterialcell. The invention further relates to said endolysin polypeptide for medical use, preferably for treating an individual suffering from a condition associated withinfection.

Endolysin polypeptide

The invention relates to the field of medicine, specifically to the field of treatment of dermatitis or eczema, even more specifically to the field of treatment of atopic dermatitis. The invention relates to a novel composition and a novel kit of parts, both comprising an anti-inflammatory compound and a compound specifically targeting a bacterial cell, preferably a gram positive bacterial cell. The invention further relates to said composition and/or kit of parts for medical use, preferably for treating an individual suffering from eczema.

Combination treatment for atopic dermatitis

The invention relates to a polypeptide, a corresponding nucleic acid molecule, a construct and/or vector and/or cell comprising such nucleic acid molecule and/or a composition comprising said polypeptide, nucleic acid molecule, construct, vector and/or cell. The invention further relates to such composition for medical use, preferably for use in treating an infectious disease. Furthermore, the invention relates to the use of said polypeptide, nucleic acid molecule, construct, vector, cell and/or composition as an antimicrobial, preferably as a food additive or disinfectant, or for detecting bacteria, preferably in a diagnostic application.

Polypeptide

The invention relates to the field of microbiology, specifically to a combination of a source of a first enzymatic active domain and a source of a second enzymatic active domain and to a composition comprising said combination. The invention further relates to a composition comprising said combination for use as a medicament, to the use of said composition as an antimicrobial agent and to a method for controlling microbial contamination in a food- or feed product, on and/or in food- or feed processing equipment, on and/or in food- or feed containers.

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Zurich, Switzerland

Fritz Eichenseher