Bracco International Bv

Sintetica S.a.

Friedrich Cavagna

Herve Tournier

Roland Hyacinthe

Suspensions of either echogenic or magnetic particles in aqueous bioadhesive carriers effectively improve imaging by echography, respectively NMRI, of the digestive tract. Affinity of the compositions for the gastric mucosa can be adapted to the needs by appropriately selecting the carrier in function to inherent bioadhesive capacity: this technique leads to improved visualization of selected portions of the lumen.

Polymers and copolymers of acrylic acid MRI of the digestive tract of

Mucoadhesive compositions for increasing the ultrasonic image contrast

Compositions for increasing the image contrast in diagnostic

Method of making an ingestible composition useful as a contrast enhancing agent in ultrasonic imaging of the digestive tract of humans and animals, wherein the composition has microballoons as contrast enhancing particles bound to an organic carrier phase, which when hydrated has an adhesive affinity for the gastrointestinal mucosa. Method includes grafting a silane coupler having at least two reactive functions to the microballoons through one of the reactive functions and binding the grafted microballoons to the carrier phase through another reactive function.

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Vicenza, Italy

Friedrich Cavagna