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Albert-Ludwigs-Universitaet Freiburg

Universitaet Fuer Bodenkultur Wien

Albert-Ludwigs-Universitat Freiburg

Universitat Fur Bodenkultur Wien

Precisionbiotics Group Limited

Altmann, Friedrich

Friedrich Altmann

Jan Mucha

Erika Staudacher

Josef Glossl

Haralt Leiter

Ralf Reski

Eva Decker

Juliana Parsons

Josef Glössl

Johannes Stadlmann

Richard Strasser

Lukas Mach

Iain B Wilson

Manuela Graf

Herta Steinkellner

Stephan Plattner

Paul Kosma

Liam O'mahony

The field of the invention relates to a method for the production of a recombinant protein in a plant-based system comprising the steps of providing a plant-based system comprising a modulation for a plant endogenous prolyl-4-hydroxylase gene, delivering a gene encoding the recombinant protein into the plant-based system, and cultivating the plant-based system for the expression of the gene encoding the recombinant protein. The field of the invention further relates to a recombinant protein, which has been produced in a plant-based system. A plant-based system and use of the recombinant protein are also provided.

Modified expression of prolyl-4-hydroxylase in physcomitrella patens

A DNA molecule is provided which comprises a sequence according to SEQ ID NO: 1 having an open reading frame from base pair 211 to base pair 1740 or having at least 50% homology to the above-indicated sequence, or hybridizing with the above-indicated sequence under stringent conditions, or comprising a sequence which has degenerated to the above-indicated DNA sequence because of the genetic code, the sequence coding for a plant protein having fucosyltransferase activity or being complementary thereto.

Fucosyl transferase gene

A DNA molecule is provided which comprises a sequence according to SEQ ID NO: 8 having an open reading frame from base pair 227 to base pair 1831 or having at least 50% homology to the above-indicated sequence, or hybridizing with the above-indicated sequence under stringent conditions, or comprising a sequence which has degenerated to the above-indicated DNA sequence because of the genetic code, the sequence coding for a plant protein having &#x3b2;1,2-xylosyltransferase activity or being complementary thereto.

&#x3b2;1,2-xylosyltransferase-gene from arabidopsis

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Vienna, Austria

Friedrich Altmann