Boehringer Mannheim Gmbh

Friedhelm Vieth

Sigmar Klose

Manfred Pasch

Helmut Schlumberger

Wolfgang Kleemann

Herbert Buschek

Wolfgang Kleeman

The present invention provides a device for rinsing out a substance present in a zone (d) with a liquid rinsing agent in several rinsing steps and for transferring the rinsing agent emerging from the zone (d) in the last rinsing step to a cuvette (K), wherein the zone (d) is present on a rotor (R) of variable speed of rotation, radially inwardly of the zone (d) on the rotor (R) there is provided a pump chamber (PK) for the rinsing agent which is connected with the zone (d) via a valve chamber (VK2) which fills, under the action of centrifugal force, above a predetermined speed of rotation, from the pump chamber (PK) and empties below the predetermined speed of rotation into the zone (d) and the zone (d) is connected with the cuvette (K) via a pipe (4) which, in one section, the axis of which has a component directed radially outwardly, is directed into a waste chamber (AK).

Device for rinsing out a substance present in a zone

In a process for carrying out an analytical determination by mixing and incubating a sample liquid with at least one dry reagent which is soluble therein to form a reaction mixture liquid and measuring a parameter in the reaction mixture liquid, the sample liquid is first transported along a transport path to the soluble dry reagent and the resulting reaction mixture liquid then further transported along the transport path. The further transporting of the reaction mixture liquid along the transport path is under the influence of a force-change cycle in which centrifugal force and a further force alternately predominate to determine the direction of the further transporting along the transport path. At least one further liquid is transported on another path, part of which is separate from and part of which is common with the transport path, by the force-change cycle in such a manner that at least two of the liquids pass through the common part of the transport path chronologically separated.

Process and device for carrying out analytical determinations

A process and a device for the centrifugal control and mixing of a limited volumes of fluid, especially in the rotor of a centrifugal analyzer, has at least one baffle chamber, in a flow canal for the fluid the volume of which is greater than the volume of fluid. It is so shaped that, when the device is rotated at a sufficiently high first speed of rotation, the fluid remains in it. An outlet canal is connected to the baffle chamber the fluid. At least a part thereof lies closer to the axis of rotation than the fluid surface during the rotation with the first speed of rotation. The walls of the outlet canal consist of a material which is wettable by the fluid and, in combination therewith, have cross-section which forces the fluid out of the baffle chamber; by boundary surface force when the device is rotated at a second, slower speed.

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Haunshofen, Germany

Friedhelm Vieth