Henkel Kommanditgesellschaft Auf Aktien

Henkel Kgaa

Friedhelm Bartnik

Hinrich Moller

Siegfried Wallat

Albrecht Weiss

Joachim Schindler

Rolf Schmid

Wolfgang Pittermann

Wolfgang Ritter

Klaus Hachmann

Karl Lintner

Use of fluid to solid oligomeric esters of lactic acid and/or glycolic acid and dermatologically compatible derivatives thereof as resorbable carriers and/or film formers in preparations for covering undamaged and/or damaged areas of human or animal skin.

Preparations for covering undamaged and/or damaged areas of human or

Arene-carboxylic acid derivatives as antiseborrheic additives for

Process for the preparation of acid stable protease having a broad activity spectrum in high yields from mutants of the fungus Aspergillus, and the mutants used therein.

Acid stable protease from mutants of genus Aspergillus

This invention relates to topical cosmetic preparations. More particularly, this invention relates to a topical cosmetic preparation for the treatment of oily hair and seborrheic skin which comprises an effective amount of at least one compound of the formula ##STR1## wherein R.sub.1, R.sub.2, and R.sub.3, any of which may be the same or different, each represent hydrogen, hydroxyl, or --OR.sub.4, where R.sub.4 is an alkyl of from 1 to 6 carbon atoms or a substituted or unsubstituted benzyl, or two of the groups R.sub.1, R.sub.2, and R.sub.3 represent methylenedioxy; X is a substituted or unsubstituted alkylene of from 1 to 3 carbon atoms; and Y is --COOH, --CN, --CONR.sub.5 R.sub.6, or --COOR.sub.7, where R.sub.5 and R.sub.6 each represent hydrogen, alkyl of from 1 to 6 carbon atoms, or substituted or unsubstituted aryl, or aralkyl, or together with the nitrogen atom R.sub.5 and R.sub.6 represent a heterocycle, and R.sub.7 is an alkyl of from 1 to 6 carbon atoms or a substituted or unsubstituted aralkyl.

Topical cosmetic preparations for the treatment of oily hair and

Process for the preparation of acid stable protease having a broad activity spectrum by culturing selected mutants of Rhizopus rhizopodiformis CBS 227.75 under aerobic conditions in a nutrient medium containing assimilable carbon and nitrogen sources, at a pH between 3 and 7 and at a temperature between 25.degree. C. and 50.degree. C., and separating the resulting protease enzyme; the mutants used in the process together with a process for preparation of the mutants.

Acid stable protease from mutants of genus Rhizopus

A topical cosmetic preparation for the treatment of seborrhea containing an antiseborrheically effective amount of at least one compound having the formula ##STR1## wherein Ar represents a member selected from the group consisting of phenyl, phenyl substituted with at least one group selected from the group consisting of alkyl having from 1 to 4 carbon atoms, alkoxy having from 1 to 4 carbon atoms, hydroxy and halo, naphthyl and heteroaromatic radical having from 4 to 5 carbon atoms in the cycle, and R represents a member selected from the group consisting of hydrogen, alkyl having from 1 to 4 carbon atoms, alkanoyl having from 1 to 4 carbon atoms, aryl and arylcarbonyl, where aryl has the same meaning as Ar, as an antiseborrheic, and further containing conventional vehicles and additives. The invention also relates to the process for reducing sebaceous cell sebum production employing said topical cosmetic preparation.

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Dusseldorf, Germany

Friedhelm Bartnik