Boehringer Mannheim Gmbh

Roche Diagnostics Operations, Inc.

Roche Diagnostics Gmbh

F. Hoffmann-la Roche Ag

Friedemann Krause

Johann Karl

Helmut Lenz

Herbert Andres

Dirk Block

Ursula-Henrike Wienhues-Thelen

Sigmar Klose

Thomas Walter

Fabian Model

Michael Tacke

Wolfgang Rollinger

Christian Zaugg

Julia Riedlinger

Hans Hornauer

Marie-Luise Hagmann

Norbert Wild

Vinzent Rolny

Sandra Rutz

Andrea Geistanger

Ruediger Laubender

Johann Berger

Peter Finckh

Andreas Gfrorer

Ursula Garczarek

Farshid Dayyani

Paul Delmar

Thomas Muley

Felix Herth

Ying He

Birgit Wehnl

Michael Thierolf

Achim Escherich

Stefan Scherer

Hans-Peter Brunner

Silke Lassmann

Baerbel Porstmann

Martin Werner

Manuela Poignee

Verena Lutz

Dorothee Foernzler

Michael Pfeffer

A computer-implemented method for determining failures in laboratory equipment comprising: a) receiving a desired probability of false rejection (P̌) and a desired error detection rate (Ě), such as a desired probability of error detection (P̌), relating to one or more QC levels (J) of quality control (QC) samples to be processed by the equipment; b) setting a number of runs (R) to one; c) calculating an error detection rate (Ê) based at least partially on R; d) determining if Êis below Ě, and if so: increase R by one, and repeat steps c) to d), and if not: define a rule for determining failures in the laboratory equipment based, at least partially, on R; e) receiving or collecting standardized QC results; f) applying the rule defined in step d) to the standardized QC results; g) determining failures in the equipment, if the standardized QC results comply with the rule.

Computerized method and laboratory equipment for fast detection of failure in laboratory equipment

The present disclosure relates to a method of identifying an individual having non-small cell lung carcinoma as to be treated by chemotherapy based on marker molecules cytokeratin-19 fragments (CYFRA 21-1) and carcinoembryonic antigen (CEA) as well as the use of the marker molecules for the identification of an individual to be treated by chemotherapy.

Methods of identifying an individual to be treated by chemotherapy based on cytokeratin-19 fragments (CYFRA 21-1) and carcinoembryonic antigen (CEA) marker molecules and related uses

A solid phase with at least one test area is described which contains reagents for the detection of at least one analyte in a sample, wherein the solid phase additionally comprises at least one control area for the detection of interfering reactions.

Use of check surfaces for identifying disturbing samples in a detection procedure

The present invention relates to a method and a device for metering liquids, wherein the volume of a droplet of a sample liquid is determined by means of optical measuring. The liquid to be metered is brought into contact with a transfer element so that a droplet adheres to the transfer element. The transfer element and the liquid adhering thereto are illuminated from one or several directions and the resulting images are displayed on an optical sensor. The liquid volume is determined on the basis of these images. Metering is accomplished by transferring the liquid volume adhering to the transfer element into an analysis vessel.

Method and device for metering liquids

Apparatus for the detection of a phase boundary (10) in a transparent measuring tube (9), in particular of a liquid level in a rising tube (11) (LLD, Liquid Level Detector). The rising tube (11) is illuminated by an illumination device (15) and the light passing through the rising tube (11) is received by a light reception device (17) which converts it into signals dependent on the spatial distribution of the light intensity. A data processing unit (7) is used for processing the signals from the light reception device (17) into information on the height of the liquid level (10) in the rising tube (11). In such an apparatus very accurate detection can be achieved even for weakly and differently coloured liquids in very thin capillary-shaped rising tubes by means of an illumination device (15) which is designed for the spatially steady illumination of the rising tube (11), in particular with diffuse light, the light reception device (17) comprising an optical imaging system (18) for generating an image of the rising tube (11) in an image plane (19) and a row (20) of closely spaced light-sensitive elements in the image plane.

Apparatus for the detection of a fluid phase boundary in a transparent

Method for analysis of a medical sample

Growing community of inventors

Penzberg, Germany

Friedemann Krause